PMID- 21397077
OWN - NLM
STAT- MEDLINE
DCOM- 20110701
LR  - 20110314
IS  - 1873-4324 (Electronic)
IS  - 0003-2670 (Linking)
VI  - 689
IP  - 2
DP  - 2011 Mar 18
TI  - Orthogonal array design for the optimization of hollow fiber protected 
      liquid-phase microextraction of salicylates from environmental waters.
PG  - 219-25
LID - 10.1016/j.aca.2011.01.045 [doi]
AB  - In the present study, a three phase-based hollow fiber protected liquid-phase 
      microextraction (HF-LPME) method combined with high-performance liquid 
      chromatography (HPLC) for the determination of salicylates in environmental 
      waters was developed. The HF-LPME procedure was optimized by an L(16)(4(5)) 
      orthogonal array experimental design (OAD) with five factors at four levels. 
      Under the optimal extraction condition (pHs of donor and receiving phases of 3.0 
      and 6.2, respectively, extraction time of 45 min, stirring speed of 1000 rpm, and 
      salt addition of 20% (w/v)), salicylates could be determined in a linear range 
      from 0.025 to 1.0 mug mL(-1) with a good correlation (r(2)>0.9930). The limits of 
      detection (LODs) ranged between 0.6 ng mL(-1) and 1.2 ng mL(-1) for the target 
      analytes. The relative standard deviations (RSDs) of intra-day and inter-day were 
      in the range of 0.64-14.58% and 0.16-15.45%, respectively. This procedure 
      afforded a convenient, sensitive, accurate and cost-saving operation with high 
      extraction efficiency for the model analytes. The method was applied 
      satisfactorily to the determination of salicylates in two environmental waters.
CI  - Copyright (c) 2011 Elsevier B.V. All rights reserved.
FAU - Zhang, Cong
AU  - Zhang C
AD  - Tongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan, 
      Hubei, China.
FAU - Ye, Lei
AU  - Ye L
FAU - Xu, Li
AU  - Xu L
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20110127
PL  - Netherlands
TA  - Anal Chim Acta
JT  - Analytica chimica acta
JID - 0370534
RN  - 0 (Salicylates)
RN  - 0 (Solvents)
RN  - 0 (Water Pollutants, Chemical)
SB  - IM
MH  - Analytic Sample Preparation Methods
MH  - Chromatography, High Pressure Liquid/*methods
MH  - Hydrogen-Ion Concentration
MH  - Salicylates/*analysis/chemistry/isolation & purification
MH  - Solvents/chemistry
MH  - Water Pollutants, Chemical/*analysis/chemistry/isolation & purification
EDAT- 2011/03/15 06:00
MHDA- 2011/07/02 06:00
CRDT- 2011/03/15 06:00
PHST- 2010/11/06 00:00 [received]
PHST- 2011/01/19 00:00 [revised]
PHST- 2011/01/20 00:00 [accepted]
PHST- 2011/03/15 06:00 [entrez]
PHST- 2011/03/15 06:00 [pubmed]
PHST- 2011/07/02 06:00 [medline]
AID - S0003-2670(11)00133-4 [pii]
AID - 10.1016/j.aca.2011.01.045 [doi]
PST - ppublish
SO  - Anal Chim Acta. 2011 Mar 18;689(2):219-25. doi: 10.1016/j.aca.2011.01.045. Epub 
      2011 Jan 27.