PMID- 21397514
OWN - NLM
STAT- MEDLINE
DCOM- 20120306
LR  - 20191210
IS  - 1873-734X (Electronic)
IS  - 1010-7940 (Linking)
VI  - 40
IP  - 5
DP  - 2011 Nov
TI  - Functional outcome of anatomic correction of corrected transposition of the great 
      arteries.
PG  - 1227-34
LID - 10.1016/j.ejcts.2011.01.077 [doi]
AB  - OBJECTIVE: Anatomic correction of corrected transposition of the great arteries, 
      utilizing the morphologic left ventricle as a systemic pumping chamber, is 
      considered the preferred method. The purpose of the study was to analyze the 
      intermediate functional outcome following anatomical correction. METHODS: Between 
      1997 and 6/2010, 23 patients with corrected transposition of the great arteries 
      and associated lesions underwent anatomical correction. Seventeen (74%) and six 
      patients (26%) had situs solitus S,L,L and situs invs I,D,D, respectively. 
      Fifteen patients (65%) had undergone 18 palliations before the corrective 
      operation. The median age at palliation was 0.23 years, with a range of 0.016-8.4 
      years. A corrective, modified Senning-arterial switch procedure was performed in 
      nine patients, 13 patients underwent a modified Senning-Rastelli procedure, and 
      in one patient a combination of modified Senning and aortic translocation 
      (Bex/Nikaidoh) was used. The median age at the corrective operation was 2 years 
      (from 0.3 to 15.7 years). RESULTS: There was no mortality or heart transplant 
      within the mean follow-up of 3.4 years. Freedom from reintervention was 77% at 5 
      years. There were no signs of obstruction of the systemic and pulmonary venous 
      tunnels. The function of both ventricles was normal in all patients, even in the 
      four patients who required retraining of the left ventricle. Mild aortic 
      regurgitation was noticed in three patients. Preoperatively detected significant 
      tricuspid regurgitation either disappeared or became trivial after the operation 
      in all the six patients. All patients except two are in sinus rhythm; one patient 
      is pacemaker-dependent preoperatively and one is pacemaker-dependent 
      postoperatively. There were no clinically apparent neurological problems. All 
      patients, but one, are in the New York Heart Association (NYHA) class I. 
      CONCLUSIONS: Anatomic correction of corrected transposition of the great arteries 
      can be performed in selected patients without mortality and with acceptable 
      morbidity. The mid-term functional outcome is excellent, resulting in normal 
      ventricular function, even in retrained left ventricles, and minimal incidence of 
      complete heart block. The long-term function of the aortic valve, 
      intraventricular tunnels, conduits, and ventricles requires close surveillance.
CI  - Copyright (c) 2011 European Association for Cardio-Thoracic Surgery. Published by 
      Elsevier B.V. All rights reserved.
FAU - Hraska, Viktor
AU  - Hraska V
AD  - German Pediatric Heart Centre, Asklepios Clinic Sankt Augustin, Arnold Janssen 
      Str. 29, 53757 Sankt Augustin, Germany. v.hraska@asklepios.com
FAU - Mattes, Angela
AU  - Mattes A
FAU - Haun, Christoph
AU  - Haun C
FAU - Blaschczok, Hedwiga Christine
AU  - Blaschczok HC
FAU - Photiadis, Joachim
AU  - Photiadis J
FAU - Murin, Peter
AU  - Murin P
FAU - Zartner, Peter
AU  - Zartner P
FAU - Asfour, Boulos
AU  - Asfour B
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
DEP - 20110312
PL  - Germany
TA  - Eur J Cardiothorac Surg
JT  - European journal of cardio-thoracic surgery : official journal of the European 
      Association for Cardio-thoracic Surgery
JID - 8804069
SB  - IM
CIN - Eur J Cardiothorac Surg. 2011 Nov;40(5):1235. PMID: 21515064
MH  - Adolescent
MH  - Aortic Valve Insufficiency/etiology
MH  - Cardiopulmonary Bypass
MH  - Child
MH  - Child, Preschool
MH  - Disease-Free Survival
MH  - Female
MH  - Heart Defects, Congenital/surgery
MH  - Humans
MH  - Infant
MH  - Male
MH  - Reoperation
MH  - Retrospective Studies
MH  - Transposition of Great Vessels/physiopathology/*surgery
MH  - Treatment Outcome
MH  - Ventricular Function/physiology
MH  - Ventricular Outflow Obstruction/surgery
EDAT- 2011/03/15 06:00
MHDA- 2012/03/07 06:00
CRDT- 2011/03/15 06:00
PHST- 2010/08/31 00:00 [received]
PHST- 2011/01/24 00:00 [revised]
PHST- 2011/01/31 00:00 [accepted]
PHST- 2011/03/15 06:00 [entrez]
PHST- 2011/03/15 06:00 [pubmed]
PHST- 2012/03/07 06:00 [medline]
AID - S1010-7940(11)00154-0 [pii]
AID - 10.1016/j.ejcts.2011.01.077 [doi]
PST - ppublish
SO  - Eur J Cardiothorac Surg. 2011 Nov;40(5):1227-34. doi: 
      10.1016/j.ejcts.2011.01.077. Epub 2011 Mar 12.