PMID- 21397777
OWN - NLM
STAT- MEDLINE
DCOM- 20110629
LR  - 20221207
IS  - 1879-114X (Electronic)
IS  - 0149-2918 (Linking)
VI  - 33
IP  - 1
DP  - 2011 Jan
TI  - Concurrent control of blood glucose, body mass, and blood pressure in patients 
      with type 2 diabetes: an analysis of data from electronic medical records.
PG  - 110-20
LID - 10.1016/j.clinthera.2011.01.018 [doi]
AB  - OBJECTIVE: This cross-sectional study describes glycemic, body mass, and blood 
      pressure (BP) control in patients with type 2 diabetes mellitus (T2DM) in an 
      ambulatory care-based database of electronic medical records (EMRs). METHODS: 
      Patients aged >/=18 years with T2DM documented in 2008 and with glycosylated 
      hemoglobin (HbA(1c)) value, body mass index (BMI), and BP charted within 90 days 
      before or after T2DM documentation were identified using the General Electric 
      Centricity EMR research database. Control of glycemia (controlled, <7.0%; 
      uncontrolled, >/=7.0% [intermediate, 7.0%- <9.0%; poor, >/=9.0%]), body mass 
      (nonobese, <30 kg/ m(2); obese, >/=30 kg/m(2) [intermediate, 30-<35 kg/m(2); poor, 
      >/=35 kg/m(2)]), and BP (controlled, <130/<80 mm Hg; uncontrolled, >/=130/>/=80 mm Hg 
      [intermediate, 130-<160/80-<100 mm Hg; poor, >/=160/>/=100 mm Hg]) was identified, 
      and patients were stratified by level of control individually and in combination. 
      Comorbidities and antidiabetic and antihypertensive treatments prescribed in the 
      year before the index date were identified in the EMR. RESULTS: The mean (SD) age 
      of the cohort (N = 49,560) was 60.9 (12.4) years; 51.5% were female. A minority 
      had controlled glycemia (36.4%), body mass (30.2%), and/or BP (36.4%). Of those 
      with controlled glycemia and body mass, 44.8% also had controlled BP, 
      representing 5.5% of the overall study population. CONCLUSIONS: Despite the 
      potential selection bias, a minority of patients in this cross-sectional study 
      were at HbA(1c), BP, or BMI goals, and even fewer gained control of all 3 of 
      these risk factors. More intensive T2DM treatment with complementary efforts to 
      manage body mass and BP is warranted in this population.
CI  - Copyright (c) 2011 Elsevier HS Journals, Inc. Published by EM Inc USA. All rights 
      reserved.
FAU - McAdam-Marx, Carrie
AU  - McAdam-Marx C
AD  - Department of Pharmacotherapy, University of Utah, Salt Lake City, Utah, USA. 
      carrie.mcadammarx@pharm.utah.edu
FAU - Bouchard, Jonathan
AU  - Bouchard J
FAU - Aagren, Mark
AU  - Aagren M
FAU - Conner, Chris
AU  - Conner C
FAU - Brixner, Diana I
AU  - Brixner DI
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Clin Ther
JT  - Clinical therapeutics
JID - 7706726
RN  - 0 (Antihypertensive Agents)
RN  - 0 (Blood Glucose)
RN  - 0 (Glycated Hemoglobin A)
RN  - 0 (Hypoglycemic Agents)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Ambulatory Care
MH  - Antihypertensive Agents/therapeutic use
MH  - Blood Glucose/*drug effects
MH  - Blood Pressure/*drug effects
MH  - Body Mass Index
MH  - Cross-Sectional Studies
MH  - Databases, Factual
MH  - Diabetes Mellitus, Type 2/complications/*drug therapy
MH  - Electronic Health Records
MH  - Female
MH  - Glycated Hemoglobin/metabolism
MH  - Humans
MH  - Hypoglycemic Agents/therapeutic use
MH  - Male
MH  - Middle Aged
MH  - Risk Factors
MH  - Selection Bias
EDAT- 2011/03/15 06:00
MHDA- 2011/06/30 06:00
CRDT- 2011/03/15 06:00
PHST- 2010/11/22 00:00 [accepted]
PHST- 2011/03/15 06:00 [entrez]
PHST- 2011/03/15 06:00 [pubmed]
PHST- 2011/06/30 06:00 [medline]
AID - S0149-2918(11)00025-7 [pii]
AID - 10.1016/j.clinthera.2011.01.018 [doi]
PST - ppublish
SO  - Clin Ther. 2011 Jan;33(1):110-20. doi: 10.1016/j.clinthera.2011.01.018.