PMID- 21400322
OWN - NLM
STAT- MEDLINE
DCOM- 20110912
LR  - 20161125
IS  - 1944-0057 (Electronic)
IS  - 1944-0057 (Linking)
VI  - 28
IP  - 5
DP  - 2011 May
TI  - Migration of plasticizers phthalates, bisphenol A and alkylphenols from plastic 
      containers and evaluation of risk.
PG  - 676-85
LID - 10.1080/19440049.2011.555845 [doi]
AB  - This study investigates the potential migration of plasticisers, plastic 
      components and additives from several plastic water bottles. Compounds studied 
      were phthalates (dimethyl phthalate, di-n-butyl phthalate, benzylbutyl phthalate, 
      bis(2-ethylhexyl) phthalate), bis(2-ethylhexyl) adipate, octylphenol, 
      4-nonylphenol and bisphenol A. Polycarbonate (PC), high-density polyethylene 
      (HDPE), low-density polyethylene (LDPE), polyethylene terephthalate (PET) and 
      polystyrene (PS) plastics used in the water bottling sector were tested using 
      three kinds of total or specific migration tests: (1) standard method UNE-EN ISO 
      177; (2) ultrasonic forced extraction; and (3) standard method UNE-EN 13130-1. In 
      addition, bottled waters contained in different plastic materials were analysed 
      to determine the potential migration of target compounds in real conditions. In 
      all cases, samples were solid-phase extracted using Oasis HLB 200 mg cartridges 
      and analysed using GC-MS in scan-acquisition mode. Bisphenol A and 4-nonylphenol 
      were detected in incubated samples, indicating that migration from food plastics 
      can occur at the experimental conditions tested. The total daily intake was 
      calculated according to the levels detected in bottled water and the assessment 
      of the consumers' risk was evaluated taking into consideration toxicological and 
      legislative values.
FAU - Guart, A
AU  - Guart A
AD  - Department of Environmental Chemistry, IDAEA/Consejo Superior de Investigaciones 
      Cientificas, Jordi Girona 18-26, Barcelona, Spain.
FAU - Bono-Blay, F
AU  - Bono-Blay F
FAU - Borrell, A
AU  - Borrell A
FAU - Lacorte, S
AU  - Lacorte S
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Food Addit Contam Part A Chem Anal Control Expo Risk Assess
JT  - Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & 
      risk assessment
JID - 101485040
RN  - 0 (Benzhydryl Compounds)
RN  - 0 (Endocrine Disruptors)
RN  - 0 (Phenols)
RN  - 0 (Phthalic Acids)
RN  - 0 (Plasticizers)
RN  - 0 (Polymers)
RN  - 059QF0KO0R (Water)
RN  - I03GBV4WEL (4-nonylphenol)
RN  - MLT3645I99 (bisphenol A)
SB  - IM
MH  - Benzhydryl Compounds
MH  - *Cooking and Eating Utensils
MH  - Diffusion
MH  - Drinking
MH  - Endocrine Disruptors/administration & dosage/analysis/chemistry/toxicity
MH  - Food Packaging
MH  - Gas Chromatography-Mass Spectrometry
MH  - Humans
MH  - Limit of Detection
MH  - Materials Testing/instrumentation/methods
MH  - Phenols/administration & dosage/*analysis/chemistry/toxicity
MH  - Phthalic Acids/administration & dosage/*analysis/chemistry/toxicity
MH  - Plasticizers/administration & dosage/*analysis/chemistry/toxicity
MH  - Polymers/*chemistry
MH  - Risk Assessment
MH  - Solid Phase Extraction
MH  - Solubility
MH  - Ultrasonics
MH  - Water/administration & dosage/*chemistry
EDAT- 2011/03/15 06:00
MHDA- 2011/09/13 06:00
CRDT- 2011/03/15 06:00
PHST- 2011/03/15 06:00 [entrez]
PHST- 2011/03/15 06:00 [pubmed]
PHST- 2011/09/13 06:00 [medline]
AID - 934836031 [pii]
AID - 10.1080/19440049.2011.555845 [doi]
PST - ppublish
SO  - Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2011 
      May;28(5):676-85. doi: 10.1080/19440049.2011.555845.