PMID- 21400833 OWN - NLM STAT- MEDLINE DCOM- 20110503 LR - 20110727 IS - 0047-1852 (Print) IS - 0047-1852 (Linking) VI - 69 IP - 3 DP - 2011 Mar TI - [HHV-6 encephalopathy]. PG - 423-8 AB - Primary human herpesvirus 6(HHV-6) and HHV-7 infections cause exanthem subitum. The disease is common febrile illness in infants, indeed these viruses rarely cause encephalopathy. Recently, various types of encephalopathy have been reported in the patient with HHV-6. Therefore, appropriate treatment should be developed for each type of the encephalitis. Recent data suggest that HHV-6 reactivation is associated with encephalitis, which occurred in immunocompromised patients. Typical clinical features of HHV-6 encephalitis in transplant recipients were amnesia and MRI findings in the hippocampus. Thus, HHV-6 is considered to be etiological agent for post-transplant acute limbic encephalitis. It has been suggested that either ganciclovir or foscarnet has anti-viral effect against HHV-6 in vitro. Therefore either of the two anti-viral drugs might be useful for treatment of HHV-6 encephalitis. FAU - Kawamura, Yoshiki AU - Kawamura Y AD - Department of Pediatrics, Fujita Health University School of Medicine. FAU - Yoshikawa, Tetsushi AU - Yoshikawa T LA - jpn PT - English Abstract PT - Journal Article PL - Japan TA - Nihon Rinsho JT - Nihon rinsho. Japanese journal of clinical medicine JID - 0420546 SB - IM MH - Child, Preschool MH - *Encephalitis, Viral MH - *Herpesvirus 6, Human/physiology MH - Herpesvirus 7, Human MH - Humans MH - Infant MH - *Roseolovirus Infections MH - Virus Activation EDAT- 2011/03/16 06:00 MHDA- 2011/05/04 06:00 CRDT- 2011/03/16 06:00 PHST- 2011/03/16 06:00 [entrez] PHST- 2011/03/16 06:00 [pubmed] PHST- 2011/05/04 06:00 [medline] PST - ppublish SO - Nihon Rinsho. 2011 Mar;69(3):423-8.