PMID- 21401062
OWN - NLM
STAT- MEDLINE
DCOM- 20110713
LR  - 20211020
IS  - 1520-5827 (Electronic)
IS  - 0743-7463 (Print)
IS  - 0743-7463 (Linking)
VI  - 27
IP  - 7
DP  - 2011 Apr 5
TI  - Control of poly(N-isopropylacrylamide) microgel network structure by 
      precipitation polymerization near the lower critical solution temperature.
PG  - 4142-8
LID - 10.1021/la200114s [doi]
AB  - Poly(N-isopropylacrylamide) (pNIPAm) microgels were synthesized by precipitation 
      polymerization at temperatures ranging from 37 to 45  degrees C using redox initiator 
      system ammonium persulfate (APS)/N,N,N',N'-tetramethylethylenediamine (TEMED) or 
      photoinitiator 2,2'-azobis(amidinopropane) dihydrochloride (V50). Photon 
      correlation spectroscopy (PCS) and atomic force microscopy (AFM) studies revealed 
      that spherical microgels with narrow size dispersities can be obtained with these 
      methods and that the resultant microgels have volume phase transition behaviors 
      expected from their compositions. Additionally, the low-temperature redox 
      initiator strategy produces microgels devoid of self-cross-linking, thereby 
      permitting the synthesis of completely degradable microgels when using 
      N,N'-(1,2-dihydroxyethylene)bisacrylamide (DHEA) as a cleavable cross-linker. We 
      also demonstrate the potential utility of the approach in bioconjugate syntheses; 
      in this case, avidin immobilization is demonstrated by one-pot copolymerization 
      at low temperature.
FAU - Hu, Xiaobo
AU  - Hu X
AD  - School of Chemistry & Biochemistry, Georgia Institute of Technology, Atlanta, 
      Georgia 30332, United States.
FAU - Tong, Zhen
AU  - Tong Z
FAU - Lyon, L Andrew
AU  - Lyon LA
LA  - eng
GR  - R01 GM088291/GM/NIGMS NIH HHS/United States
GR  - R01 GM088291-01/GM/NIGMS NIH HHS/United States
GR  - 1 R01 GM088291-01/GM/NIGMS NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
DEP - 20110314
PL  - United States
TA  - Langmuir
JT  - Langmuir : the ACS journal of surfaces and colloids
JID - 9882736
RN  - 0 (Acrylamides)
RN  - 0 (Acrylic Resins)
RN  - 0 (Ethylenediamines)
RN  - 0 (Polymers)
RN  - 110-18-9 (N,N,N',N'-tetramethylethylenediamine)
RN  - 25189-55-3 (poly-N-isopropylacrylamide)
RN  - 868-63-3 (N,N'-(1,2-dihydroxyethylene)bisacrylamide)
SB  - IM
MH  - Acrylamides/*chemistry
MH  - Acrylic Resins
MH  - Ethylenediamines/chemistry
MH  - Microscopy, Atomic Force
MH  - Polymerization
MH  - Polymers/*chemistry
MH  - Temperature
PMC - PMC3068749
MID - NIHMS280786
EDAT- 2011/03/16 06:00
MHDA- 2011/07/14 06:00
PMCR- 2012/04/05
CRDT- 2011/03/16 06:00
PHST- 2011/03/16 06:00 [entrez]
PHST- 2011/03/16 06:00 [pubmed]
PHST- 2011/07/14 06:00 [medline]
PHST- 2012/04/05 00:00 [pmc-release]
AID - 10.1021/la200114s [doi]
PST - ppublish
SO  - Langmuir. 2011 Apr 5;27(7):4142-8. doi: 10.1021/la200114s. Epub 2011 Mar 14.