PMID- 21402600
OWN - NLM
STAT- MEDLINE
DCOM- 20111024
LR  - 20161125
IS  - 1569-9285 (Electronic)
IS  - 1569-9285 (Linking)
VI  - 13
IP  - 1
DP  - 2011 Jul
TI  - Results of coronary artery bypass grafting alone and combined with surgical 
      ventricular reconstruction for ischemic heart failure.
PG  - 46-51
LID - 10.1510/icvts.2010.253716 [doi]
AB  - In this study, we included 236 patients with ischemic heart failure and ejection 
      fraction (EF) <35% who underwent surgical treatment. Patients were randomized in 
      two groups. There were 116 patients who underwent coronary artery bypass grafting 
      (CABG) with surgical ventricular reconstruction (SVR) and 120 patients who 
      underwent CABG alone. The hospital mortality rate was 5.8% after isolated CABG 
      and 3.5% after CABG combined with SVR. All survivors had follow-up investigation 
      from four months to five years, with a mean follow-up time of 31+/-13 months. The 
      mean New York Heart Association (NYHA) functional class decreased from 2.9+/-0.5 to 
      2.2+/-0.7 one year after CABG and from 3.1+/-0.4 to 2.0+/-0.6 one year after CABG with 
      SVR. We showed that left ventricular reconstruction significantly decreased EDV 
      from 237+/-52 to 176+/-30 and correspondingly increased EF from 32+/-6 to 39+/-9. 
      However, after isolated CABG EF did not increase significantly (32+/-7 
      preoperatively and 34+/-11 postoperatively). One- and three-year rates were 95% and 
      78% after SVR with CABG and 83% and 78% after CABG alone. Despite the more 
      aggressive surgical strategy, left ventricular reconstruction did not increase 
      operative mortality and early results were significantly effective compared with 
      coronary artery bypass grafting alone.
FAU - Marchenko, Andrey
AU  - Marchenko A
AD  - Department of Aortic and Coronary Artery Surgery, Research Institute of 
      Circulation Pathology, Novosibirsk, Russia. mammaria@mail.ru
FAU - Chernyavsky, Alexander
AU  - Chernyavsky A
FAU - Efendiev, Vidady
AU  - Efendiev V
FAU - Volokitina, Tanya
AU  - Volokitina T
FAU - Karaskov, Alexander
AU  - Karaskov A
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20110314
PL  - England
TA  - Interact Cardiovasc Thorac Surg
JT  - Interactive cardiovascular and thoracic surgery
JID - 101158399
SB  - IM
MH  - *Cardiac Surgical Procedures/adverse effects/mortality
MH  - Chi-Square Distribution
MH  - *Coronary Artery Bypass/adverse effects/mortality
MH  - Female
MH  - Heart Failure/diagnostic imaging/etiology/mortality/physiopathology/*surgery
MH  - Heart Ventricles/physiopathology/surgery
MH  - Hospital Mortality
MH  - Humans
MH  - Kaplan-Meier Estimate
MH  - Logistic Models
MH  - Male
MH  - Middle Aged
MH  - Myocardial Ischemia/complications/diagnostic 
      imaging/mortality/physiopathology/*surgery
MH  - Recovery of Function
MH  - Risk Assessment
MH  - Risk Factors
MH  - Russia
MH  - Stroke Volume
MH  - Survival Rate
MH  - Time Factors
MH  - Treatment Outcome
MH  - Ultrasonography
MH  - Ventricular Dysfunction, Left/diagnostic 
      imaging/etiology/mortality/physiopathology/*surgery
MH  - Ventricular Function, Left
EDAT- 2011/03/16 06:00
MHDA- 2011/10/25 06:00
CRDT- 2011/03/16 06:00
PHST- 2011/03/16 06:00 [entrez]
PHST- 2011/03/16 06:00 [pubmed]
PHST- 2011/10/25 06:00 [medline]
AID - icvts.2010.253716 [pii]
AID - 10.1510/icvts.2010.253716 [doi]
PST - ppublish
SO  - Interact Cardiovasc Thorac Surg. 2011 Jul;13(1):46-51. doi: 
      10.1510/icvts.2010.253716. Epub 2011 Mar 14.