PMID- 21407935 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20110714 LR - 20211020 IS - 0019-5545 (Print) IS - 1998-3794 (Electronic) IS - 0019-5545 (Linking) VI - 42 IP - 2 DP - 2000 Apr TI - Rave drug (ecstasy) and selective serotonin reuptake inhibitor anti-depressants. PG - 195-7 AB - 3, 4 Methylenedioxymethamphetamine (MDMA) also known as Ecstasy is a common recreational drug of abuse and reports of abuse of tricyclic antidepressants are also known. We report two cases of misuse of selective serotonin re-uptake inhibitors (SSRIs) antidepressants in combination with Ecstasy and their beneficial subjective effects experienced by misusers. We hypothesise the probable underlying pharmacological reasons and recommend its use in the treatment of neurotoxic effects of MDMA. FAU - Singh, A N AU - Singh AN AD - A.N. SINGH, Consultant Psychiatrist, South Lincolnshire Healthcare NHS Trust, Beaconfield Centre, Beacon Lane, Grantham Lines, NG319DF, UK. FAU - Catalan, J AU - Catalan J LA - eng PT - Journal Article PL - India TA - Indian J Psychiatry JT - Indian journal of psychiatry JID - 0013255 PMC - PMC2957712 OTO - NOTNLM OT - MDMA OT - SSRI's OT - antidepressant OT - treatment potential EDAT- 2000/04/01 00:00 MHDA- 2000/04/01 00:01 PMCR- 2000/04/01 CRDT- 2011/03/17 06:00 PHST- 2011/03/17 06:00 [entrez] PHST- 2000/04/01 00:00 [pubmed] PHST- 2000/04/01 00:01 [medline] PHST- 2000/04/01 00:00 [pmc-release] AID - IJPsy-42-195 [pii] PST - ppublish SO - Indian J Psychiatry. 2000 Apr;42(2):195-7.