PMID- 21408130 OWN - NLM STAT- MEDLINE DCOM- 20110621 LR - 20211020 IS - 1935-2735 (Electronic) IS - 1935-2727 (Print) IS - 1935-2727 (Linking) VI - 5 IP - 3 DP - 2011 Mar 8 TI - Incremental cost of conducting population-based prevalence surveys for a neglected tropical disease: the example of trachoma in 8 national programs. PG - e979 LID - 10.1371/journal.pntd.0000979 [doi] LID - e979 AB - BACKGROUND: Trachoma prevalence surveys provide the evidence base for district and community-wide implementation of the SAFE strategy, and are used to evaluate the impact of trachoma control interventions. An economic analysis was performed to estimate the cost of trachoma prevalence surveys conducted between 2006 and 2010 from 8 national trachoma control programs in Africa. METHODOLOGY AND FINDINGS: Data were collected retrospectively from reports for 165 districts surveyed for trachoma prevalence using a cluster random sampling methodology in Ethiopia, Ghana, Mali, Niger, Nigeria, Sudan, Southern Sudan and The Gambia. The median cost per district survey was $4,784 (inter-quartile range [IQR] = $3,508-$6,650) while the median cost per cluster was $311 (IQR = $119-$393). Analysis by cost categories (personnel, transportation, supplies and other) and cost activity (training, field work, supervision and data entry) revealed that the main cost drivers were personnel and transportation during field work. CONCLUSION: Population-based cluster random surveys are used to provide the evidence base to set objectives and determine when elimination targets have been reached for several neglected tropical diseases, including trachoma. The cost of conducting epidemiologically rigorous prevalence surveys should not be a barrier to program implementation or evaluation. FAU - Chen, Chaoqun AU - Chen C AD - Georgia Institute of Technology, Atlanta, Georgia, USA. FAU - Cromwell, Elizabeth A AU - Cromwell EA FAU - King, Jonathan D AU - King JD FAU - Mosher, Aryc AU - Mosher A FAU - Harding-Esch, Emma M AU - Harding-Esch EM FAU - Ngondi, Jeremiah M AU - Ngondi JM FAU - Emerson, Paul M AU - Emerson PM LA - eng GR - Wellcome Trust/United Kingdom PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20110308 PL - United States TA - PLoS Negl Trop Dis JT - PLoS neglected tropical diseases JID - 101291488 SB - IM MH - Africa/epidemiology MH - Humans MH - Neglected Diseases/*epidemiology/*prevention & control MH - *Population Surveillance MH - Public Health Administration/*economics MH - Retrospective Studies MH - Trachoma/*epidemiology/*prevention & control PMC - PMC3050919 COIS- The authors have declared that no competing interests exist. EDAT- 2011/03/17 06:00 MHDA- 2011/06/22 06:00 PMCR- 2011/03/08 CRDT- 2011/03/17 06:00 PHST- 2010/08/18 00:00 [received] PHST- 2011/02/04 00:00 [accepted] PHST- 2011/03/17 06:00 [entrez] PHST- 2011/03/17 06:00 [pubmed] PHST- 2011/06/22 06:00 [medline] PHST- 2011/03/08 00:00 [pmc-release] AID - 10-PNTD-RA-1470R4 [pii] AID - 10.1371/journal.pntd.0000979 [doi] PST - epublish SO - PLoS Negl Trop Dis. 2011 Mar 8;5(3):e979. doi: 10.1371/journal.pntd.0000979.