PMID- 21412795
OWN - NLM
STAT- MEDLINE
DCOM- 20110715
LR  - 20110317
IS  - 1096-9071 (Electronic)
IS  - 0146-6615 (Linking)
VI  - 83
IP  - 5
DP  - 2011 May
TI  - Viral etiology of aseptic meningitis among children in southern Iran.
PG  - 884-8
LID - 10.1002/jmv.22056 [doi]
AB  - Aseptic meningitis refers to a clinical syndrome of meningeal inflammation in 
      which bacteria cannot be identified in the cerebrospinal fluid (CSF). The viral 
      etiology and the epidemiological, clinical, and laboratory characteristics of 
      aseptic meningitis among children aged 2 months to 15 years in Shiraz, southern 
      Iran were determined. From May 2007 to April 2008, 65 patients were admitted to 
      the hospital with aseptic meningitis. Seven viruses, non-polio human 
      enteroviruses, mumps virus, herpes simplex virus (HSV), varicella-zoster virus 
      (VZV), human cytomegalovirus (HCMV), human herpes virus type 6 (HHV-6), and 
      Epstein-Barr virus (EBV) were investigated by polymerase chain reaction (PCR) 
      method. Viruses were detected in 30 (46.2%) patients in whom non-polio human 
      enterovirus and mumps virus were detected in 13 (43.3%) and 11 (36.7%), 
      respectively. The remaining 6 (20%) of the cases were caused by HSV, VZV, HCMV, 
      and HHV-6. Haemophilus influenzae and non-polio human enterovirus were detected 
      in one patient simultaneously. Viral meningitis was found to be more frequent 
      during spring and summer. The majority (66.6%) of the patients were treated in 
      the hospital for 10 days and had received antibiotics in the case of bacterial 
      meningitis. Rapid diagnosis of viral meningitis using PCR testing of CSF can help 
      shorten hospitalization, and avoid the unnecessary use of antibiotics.
CI  - Copyright (c) 2011 Wiley-Liss, Inc.
FAU - Hosseininasab, Ali
AU  - Hosseininasab A
AD  - Department of Pediatrics, Kerman University of Medical Sciences, Kerman, Iran.
FAU - Alborzi, Abdolvahab
AU  - Alborzi A
FAU - Ziyaeyan, Mazyar
AU  - Ziyaeyan M
FAU - Jamalidoust, Marzieh
AU  - Jamalidoust M
FAU - Moeini, Mahsa
AU  - Moeini M
FAU - Pouladfar, Gholamreza
AU  - Pouladfar G
FAU - Abbasian, Amin
AU  - Abbasian A
FAU - Kadivar, Mohamad Rahim
AU  - Kadivar MR
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Med Virol
JT  - Journal of medical virology
JID - 7705876
SB  - IM
MH  - Adolescent
MH  - Child
MH  - Child, Preschool
MH  - Female
MH  - Hospitalization
MH  - Humans
MH  - Infant
MH  - Iran/epidemiology
MH  - Length of Stay/statistics & numerical data
MH  - Male
MH  - Meningitis, Viral/*epidemiology/pathology/*virology
MH  - Prevalence
MH  - Risk Factors
MH  - Seasons
MH  - Viruses/*classification/*isolation & purification
EDAT- 2011/03/18 06:00
MHDA- 2011/07/16 06:00
CRDT- 2011/03/18 06:00
PHST- 2011/03/18 06:00 [entrez]
PHST- 2011/03/18 06:00 [pubmed]
PHST- 2011/07/16 06:00 [medline]
AID - 10.1002/jmv.22056 [doi]
PST - ppublish
SO  - J Med Virol. 2011 May;83(5):884-8. doi: 10.1002/jmv.22056.