PMID- 21423465 OWN - NLM STAT- MEDLINE DCOM- 20110707 LR - 20211020 IS - 1526-6702 (Electronic) IS - 0730-2347 (Print) IS - 0730-2347 (Linking) VI - 38 IP - 1 DP - 2011 TI - Usefulness of the Echocardiographic Multi-Parameter Score (EMPS) in evaluating left ventricular global heart function. PG - 27-34 AB - In this study, we established a new index by combining several echocardiographic parameters to quantify heart failure. We selected 233 consecutive patients who underwent both echocardiographic and plasma B-type natriuretic peptide (BNP) tests within 24 hours after referral for suspected heart failure. The echocardiographic parameters included systolic function, diastolic function, left ventricular chamber remodeling, valvular lesions, systolic pulmonary arterial pressure, and regional wall-motion abnormality. Each factor was scored from 1 to 3 points according to its severity. The total point from these 6 factors is the echocardiographic multi-parameter score (EMPS).The EMPS for 37, 51, 77, and 38 patients from New York Heart Association (NYHA) functional classes I, II, III, and IV, respectively, were 1.24 +/- 1.25, 2.98 +/- 1.83, 5.96 +/- 2.38, and 7.21 +/- 1.99, which were significantly different from the mean score of our 30 normal patients (P <0.001). Sensitivity, specificity, and accuracy of an EMPS >/=2 for diagnosis of NYHA classes II to IV were 93%, 83%, and 89%, respectively. The area under the receiver operating characteristic curve was 0.94 (95% confidence interval, 0.92-0.98; P <0.001). There were significant correlations between logBNP and EMPS (r=0.81, P <0.001) or Tei index (r=0.48, P <0.001). In multilinear regression analysis, EMPS, early/late transmitral flow, and peak systolic velocity from tissue Doppler were entered into the model (P <0.001). The standardized regression coefficient (r=0.68) of EMPS was much higher than those of the other 2 factors, which suggests that EMPS is a powerful predictor of BNP levels. FAU - Zhou, Bingyuan AU - Zhou B AD - Department of Cardiology, the First Affiliated Hospital of Soochow University, Suzhou 215006, People's Republic of China. FAU - Yang, Junhua AU - Yang J FAU - Yang, Xiangjun AU - Yang X FAU - He, Yongming AU - He Y FAU - Zhao, Caiming AU - Zhao C FAU - Xu, Sudan AU - Xu S FAU - Wang, Huifeng AU - Wang H LA - eng PT - Evaluation Study PT - Journal Article PL - United States TA - Tex Heart Inst J JT - Texas Heart Institute journal JID - 8214622 RN - 0 (Biomarkers) RN - 114471-18-0 (Natriuretic Peptide, Brain) SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - Biomarkers/blood MH - Blood Pressure MH - China MH - *Echocardiography, Doppler MH - Female MH - Heart Failure/blood/*diagnostic imaging/physiopathology MH - Humans MH - Male MH - Middle Aged MH - Myocardial Contraction MH - Natriuretic Peptide, Brain/blood MH - Pilot Projects MH - Predictive Value of Tests MH - Pulmonary Artery/diagnostic imaging/physiopathology MH - Regression Analysis MH - Retrospective Studies MH - Sensitivity and Specificity MH - Severity of Illness Index MH - *Ventricular Function, Left MH - Ventricular Remodeling MH - Young Adult PMC - PMC3060736 OTO - NOTNLM OT - Blood pres-sure OT - cardiovascular diseases/etiology OT - diagnostic techniques, cardiovas-cular OT - echocardiography/standards OT - heart failure/diagnosis/physiopathology/statistics & numerical data OT - heart function tests/methods OT - heart valve diseases/complications OT - hypertension, pulmonary OT - natriuretic peptide, brain OT - predictive value of tests OT - pulmonary wedge pressure OT - stroke volume OT - ventricular function, left/diagnosis/ultrasonography OT - ventricular remodeling EDAT- 2011/03/23 06:00 MHDA- 2011/07/08 06:00 PMCR- 2011/01/01 CRDT- 2011/03/23 06:00 PHST- 2011/03/23 06:00 [entrez] PHST- 2011/03/23 06:00 [pubmed] PHST- 2011/07/08 06:00 [medline] PHST- 2011/01/01 00:00 [pmc-release] AID - 0010801-201102000-00006 [pii] PST - ppublish SO - Tex Heart Inst J. 2011;38(1):27-34.