PMID- 21423684
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20110714
LR  - 20240416
IS  - 2090-0392 (Electronic)
VI  - 2011
DP  - 2011 Mar 6
TI  - Addressing the common pathway underlying hypertension and diabetes in people who 
      are obese by maximizing health: the ultimate knowledge translation gap.
PG  - 835805
LID - 10.4061/2011/835805 [doi]
LID - 835805
AB  - In accordance with the WHO definition of health, this article examines the 
      alarming discord between the epidemiology of hypertension, type 2 diabetes 
      mellitus (T2DM), and obesity and the low profile of noninvasive (nondrug) 
      compared with invasive (drug) interventions with respect to their prevention, 
      reversal and management. Herein lies the ultimate knowledge translation gap and 
      challenge in 21st century health care. Although lifestyle modification has long 
      appeared in guidelines for medically managing these conditions, this 
      evidence-based strategy is seldom implemented as rigorously as drug prescription. 
      Biomedicine focuses largely on reducing signs and symptoms; the effects of the 
      problem rather than the problem. This article highlights the evidence-based 
      rationale supporting prioritizing the underlying causes and contributing factors 
      for hypertension and T2DM, and, in turn, obesity. We argue that a primary focus 
      on maximizing health could eliminate all three conditions, at best, or, at worst, 
      minimize their severity, complications, and medication needs. To enable such 
      knowledge translation and maximizing health outcome, the health care community 
      needs to practice as an integrated team, and address barriers to effecting 
      maximal health in all patients. Addressing the ultimate knowledge translation 
      gap, by aligning the health care paradigm to 21st century needs, would constitute 
      a major advance.
FAU - Dean, Elizabeth
AU  - Dean E
AD  - Department of Physical Therapy, Faculty of Medicine, University of British 
      Columbia, Vancouver, BC, Canada V6T 1Z3.
FAU - Lomi, Constantina
AU  - Lomi C
FAU - Bruno, Selma
AU  - Bruno S
FAU - Awad, Hamzeh
AU  - Awad H
FAU - O'Donoghue, Grainne
AU  - O'Donoghue G
LA  - eng
PT  - Journal Article
DEP - 20110306
PL  - United States
TA  - Int J Hypertens
JT  - International journal of hypertension
JID - 101538881
PMC - PMC3057046
EDAT- 2011/03/23 06:00
MHDA- 2011/03/23 06:01
PMCR- 2011/03/06
CRDT- 2011/03/23 06:00
PHST- 2010/12/17 00:00 [received]
PHST- 2011/01/11 00:00 [accepted]
PHST- 2011/03/23 06:00 [entrez]
PHST- 2011/03/23 06:00 [pubmed]
PHST- 2011/03/23 06:01 [medline]
PHST- 2011/03/06 00:00 [pmc-release]
AID - 10.4061/2011/835805 [doi]
PST - epublish
SO  - Int J Hypertens. 2011 Mar 6;2011:835805. doi: 10.4061/2011/835805.