PMID- 21423887
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20110714
LR  - 20240504
IS  - 0973-2063 (Electronic)
IS  - 0973-2063 (Linking)
VI  - 5
IP  - 10
DP  - 2011 Feb 15
TI  - Phylogenetic analysis of H1N1 sequences from pandemic infections during 2009 in 
      India.
PG  - 416-21
AB  - Since April 2009, a serious pandemic infection has been rapidly spread across the 
      world. These infections are caused due to the novel swine origin influenza A 
      (H1N1) virus and hence these are commonly called as "Swine Flu". This new virus 
      is the reassortment of avian, human and swine influenza viruses and thus it has a 
      unique genome composition. There are 16 different types of hemagglutinin (HA) and 
      9 different types of neuraminidase (NA) that can be genetically and 
      antigenetically differentiated. The first influenza A virus isolated from pigs 
      was of the H1N1 subtype and these viruses have been reported to cause infection 
      in pigs in many countries. The outbreak of this virus has been transmitted from 
      pigs to humans. This new reassorted (exchange of genes) virus which is the cause 
      of 2009 pandemic infections has the ability to spread from human to human. This 
      spread of infection should be brought to an end. In this study, a phylogenetic 
      analysis of the nucleotide sequences of the RNA segments of human H1N1 viruses 
      was carried using MEGA version 4.0 to demonstrate the route map of infection to 
      India. Phylogenetic analysis of the sequences from India, published in Influenza 
      Virus Resource (a database that integrates information gathered from the 
      Influenza Genome Sequencing Project of the National Institute of Allergy and 
      Infectious diseases (NIAID) and the genbank of the (NCBI)) was retrieved and used 
      for the analysis. The results showed that the various segments of the Indian 
      isolates clustered well with the sequences from American, Asian and European 
      countries and thus indicating the transmission of viruses from these places to 
      India.
FAU - Flavia, Guntupally Balaswamy Arti
AU  - Flavia GB
AD  - Division of Medical Microbiology, Department of Microbiology, School of Life 
      Sciences, Bharathidasan University, Tiruchirappalli - 620 024, Tamilnadu, India.
FAU - Natarajaseenivasan, Kalimuthusamy
AU  - Natarajaseenivasan K
LA  - eng
PT  - Journal Article
DEP - 20110215
PL  - Singapore
TA  - Bioinformation
JT  - Bioinformation
JID - 101258255
PMC - PMC3055158
OTO - NOTNLM
OT  - H1N1 virus
OT  - India
OT  - Phylogenetic analysis
OT  - Swine Flu
EDAT- 2011/03/23 06:00
MHDA- 2011/03/23 06:01
PMCR- 2011/01/01
CRDT- 2011/03/23 06:00
PHST- 2010/07/26 00:00 [received]
PHST- 2010/08/26 00:00 [accepted]
PHST- 2011/03/23 06:00 [entrez]
PHST- 2011/03/23 06:00 [pubmed]
PHST- 2011/03/23 06:01 [medline]
PHST- 2011/01/01 00:00 [pmc-release]
AID - 009400052011 [pii]
AID - 10.6026/97320630005416 [doi]
PST - epublish
SO  - Bioinformation. 2011 Feb 15;5(10):416-21. doi: 10.6026/97320630005416.