PMID- 21430378
OWN - NLM
STAT- MEDLINE
DCOM- 20110815
LR  - 20221207
IS  - 1421-9697 (Electronic)
IS  - 0250-6807 (Linking)
VI  - 58
IP  - 1
DP  - 2011
TI  - Adherence to the Mediterranean diet in patients with type 2 diabetes mellitus and 
      HbA1c level.
PG  - 74-8
LID - 10.1159/000324718 [doi]
AB  - RATIONALE AND OBJECTIVE: The Mediterranean diet (MeDiet) has beneficial effects 
      on cardiovascular risk factors. We analyzed the association between adherence of 
      a MeDiet in patients with type 2 diabetes mellitus (T2DM) and levels of HbA1c. 
      PATIENTS AND METHODS: This was a cross-sectional study in individuals with T2DM 
      participating in the PREDIMED trial at the centre of Pamplona. Information on 
      diet was collected with a validated 14 point scale of adherence to the MeDiet and 
      blood samples were obtained to assess HbA1c levels. RESULTS: We studied 383 
      participants with T2DM, 53.4% women (mean age 69 +/- 6 years). HbA1c data were 
      available in 262 cases (mean 6.9 +/- 1.5%). Although there was a potential inverse 
      non-significant association between adherence to MeDiet and HbA1c levels after 
      adjusting for age and sex, it was not statistically significant. Multivariate 
      analysis additionally adjusted for physical activity, smoking, time of evolution 
      of the T2DM, body mass index and insulin treatment found similar findings (OR = 
      0.69, 95% CI 0.17-2.83). CONCLUSIONS: Although we found not enough evidence to 
      support that a MeDiet is associated with lower levels of HbA1c in patients with 
      T2DM, our results suggested an inverse trend. Future studies with larger sample 
      size are necessary.
CI  - Copyright (c) 2011 S. Karger AG, Basel.
FAU - Diez-Espino, Javier
AU  - Diez-Espino J
AD  - Primary Health Care Centre of Tafalla, Tafalla, Spain. 
      javier.diez.espino@cfnavarra.es
FAU - Buil-Cosiales, Pilar
AU  - Buil-Cosiales P
FAU - Serrano-Martinez, Manuel
AU  - Serrano-Martinez M
FAU - Toledo, Estefania
AU  - Toledo E
FAU - Salas-Salvado, Jordi
AU  - Salas-Salvado J
FAU - Martinez-Gonzalez, Miguel Angel
AU  - Martinez-Gonzalez MA
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20110324
PL  - Switzerland
TA  - Ann Nutr Metab
JT  - Annals of nutrition & metabolism
JID - 8105511
RN  - 0 (Glycated Hemoglobin A)
RN  - 0 (hemoglobin A1c protein, human)
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Body Mass Index
MH  - Cross-Sectional Studies
MH  - Diabetes Mellitus, Type 2/*diet therapy
MH  - *Diet, Mediterranean
MH  - Female
MH  - Glycated Hemoglobin/*analysis
MH  - Glycemic Index
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Multivariate Analysis
MH  - Randomized Controlled Trials as Topic
MH  - Risk Factors
MH  - Spain
MH  - *Surveys and Questionnaires
EDAT- 2011/03/25 06:00
MHDA- 2011/08/16 06:00
CRDT- 2011/03/25 06:00
PHST- 2010/03/24 00:00 [received]
PHST- 2011/01/30 00:00 [accepted]
PHST- 2011/03/25 06:00 [entrez]
PHST- 2011/03/25 06:00 [pubmed]
PHST- 2011/08/16 06:00 [medline]
AID - 000324718 [pii]
AID - 10.1159/000324718 [doi]
PST - ppublish
SO  - Ann Nutr Metab. 2011;58(1):74-8. doi: 10.1159/000324718. Epub 2011 Mar 24.