PMID- 21437152
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20110714
LR  - 20220410
IS  - 1178-7007 (Print)
IS  - 1178-7007 (Electronic)
IS  - 1178-7007 (Linking)
VI  - 1
DP  - 2008 Oct 14
TI  - Assessing the effect of weight and weight loss in obese persons with type 2 
      diabetes.
PG  - 13-23
AB  - The objective of this study was to assess specific areas of life in which obesity 
      affects individuals with type 2 diabetes mellitus (T2DM), and changes that obese 
      persons with T2DM experience with weight loss of varying degrees. Thirty in-depth 
      interviews were conducted in persons identified as: age >/=40 years, diagnosed with 
      T2DM for >/=2 years, on oral antihyperglycemic medications >3 months, BMI 30-35 
      kg/m(2), having attempted to lose weight in the last 2 years. Participants (60% 
      female, mean age 53 years, 53% Caucasian, mean BMI 32.2 kg/m(2)) agreed that 5% 
      weight loss, while not reflective of an ultimate goal, would be meaningful and 
      important; benefits were expected to accrue in physical functioning, 
      self-confidence, blood glucose levels, and motivation to keep losing weight. 
      Participants reported the greatest effect of weight loss on energy, physical 
      activity, mobility, pain, and clothes/appearance. Participants reported weight 
      affecting mood, with feelings of depression and frustration most commonly 
      described. This research indicates that weight loss is likely to affect 
      health-related quality of life in obese individuals with T2DM. Given the 
      purported weight loss benefits of many emerging diabetic medications, it will be 
      important to include measures of weight-related quality of life in future 
      clinical trials of these agents.
FAU - Curtis, Bradley
AU  - Curtis B
AD  - Global Health Outcomes, Eli Lilly and Co, Indianapolis, IN, USA;
FAU - Hayes, Risa P
AU  - Hayes RP
FAU - Fehnel, Sheri
AU  - Fehnel S
FAU - Zografos, Laurie
AU  - Zografos L
LA  - eng
PT  - Journal Article
DEP - 20081014
PL  - New Zealand
TA  - Diabetes Metab Syndr Obes
JT  - Diabetes, metabolic syndrome and obesity : targets and therapy
JID - 101515585
PMC - PMC3052714
OTO - NOTNLM
OT  - health-related quality of life
OT  - obesity
OT  - patient- reported outcomes
OT  - type 2 diabetes
OT  - weight loss
EDAT- 2008/01/01 00:00
MHDA- 2008/01/01 00:01
PMCR- 2008/10/14
CRDT- 2011/03/26 06:00
PHST- 2011/03/26 06:00 [entrez]
PHST- 2008/01/01 00:00 [pubmed]
PHST- 2008/01/01 00:01 [medline]
PHST- 2008/10/14 00:00 [pmc-release]
AID - dmso-1-013 [pii]
AID - 10.2147/dmso.s4237 [doi]
PST - epublish
SO  - Diabetes Metab Syndr Obes. 2008 Oct 14;1:13-23. doi: 10.2147/dmso.s4237.