PMID- 21438377
OWN - NLM
STAT- MEDLINE
DCOM- 20120213
LR  - 20161018
IS  - 1000-8713 (Print)
IS  - 1000-8713 (Linking)
VI  - 28
IP  - 12
DP  - 2010 Dec
TI  - [Application of solid phase extraction disk in the determination of acrylamide in 
      tap water].
PG  - 1196-9
AB  - A simple and fast method of solid phase extraction (SPE) disk for the 
      determination of trace acrylamide was developed. Using this new technique along 
      with high performance liquid chromatography (HPLC) and ultraviolet spectroscopy 
      (UV) detection, the feasibility of SPE disk method for rapid enrichment was 
      demonstrated in the determination of trace acrylamide in 500 mL tap water. Active 
      carbon was chosen as the adsorbent to be incorporated into the SPE disk as it 
      gave the best adsorption efficiency. Experimental parameters including solvent, 
      elution volume, elution rate, breakthrough volume were optimized to give the 
      highest efficiency of extraction. Under proper chromatographic conditions, 
      acrylamide was easily separated from other impurities. A linear relationship 
      between peak area and mass concentration in the range 0.05-0.5 mg/L of acrylamide 
      was established with a correlation coefficient of 0.998. The limit of detection 
      was 20 ng/L. The recoveries for acrylamide with different concentrations and 
      volumes ranged from 94.12% to 100.2%. The relative standard deviations (RSDs) 
      were 2.09%-4.51% (n=3). The recovery for acrylamide spiked into a tap water 
      sample was 79. 96%. The method is simple, fast, sensitive and suitable for the 
      determination of acrylamide in tap water.
FAU - Zhang, Bo
AU  - Zhang B
AD  - Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of 
      Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China.
FAU - Qi, Yue
AU  - Qi Y
FAU - Gao, Henan
AU  - Gao H
FAU - Bao, James Jianmin
AU  - Bao JJ
LA  - chi
PT  - English Abstract
PT  - Journal Article
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
RN  - 0 (Drinking Water)
RN  - 0 (Water Pollutants, Chemical)
RN  - 16291-96-6 (Charcoal)
RN  - 20R035KLCI (Acrylamide)
SB  - IM
MH  - Acrylamide/*analysis
MH  - Charcoal/chemistry
MH  - Chromatography, High Pressure Liquid/*methods
MH  - Drinking Water/*analysis
MH  - Humans
MH  - Solid Phase Extraction/*methods
MH  - Water Pollutants, Chemical/analysis
EDAT- 2011/03/29 06:00
MHDA- 2012/02/14 06:00
CRDT- 2011/03/29 06:00
PHST- 2011/03/29 06:00 [entrez]
PHST- 2011/03/29 06:00 [pubmed]
PHST- 2012/02/14 06:00 [medline]
PST - ppublish
SO  - Se Pu. 2010 Dec;28(12):1196-9.