PMID- 21440322 OWN - NLM STAT- MEDLINE DCOM- 20111017 LR - 20110607 IS - 1872-8227 (Electronic) IS - 0168-8227 (Linking) VI - 92 IP - 3 DP - 2011 Jun TI - Serum interleukin-18 binding protein increases with behavior different from IL-18 in patients with diabetic nephropathy. PG - e66-9 LID - 10.1016/j.diabres.2011.02.028 [doi] AB - We investigated alterations between serum interleukin 18 (IL-18) and IL-18 binding protein (18BP) in T2DM patients. 18 BP began to increase after IL-18 increased and reached a threshold, in which case kidney dysfunction would have developed. These data indicate that 18BP might express glomerular dysfunction more closely than IL-18. CI - Copyright (c) 2011 Elsevier Ireland Ltd. All rights reserved. FAU - Fujita, Takayuki AU - Fujita T AD - Department of Nephrology, Hypertension and Endocrinology, Nihon University School of Medicine, 30-1 Oyaguchi-kamimachi, Itabashiku, Tokyo 173-8610, Japan. tfujita@med.nihon-u.ac.jp FAU - Shimizu, Chie AU - Shimizu C FAU - Fuke, Yoshinobu AU - Fuke Y FAU - Satomura, Atsushi AU - Satomura A FAU - Abe, Masanori AU - Abe M FAU - Kaizu, Kazo AU - Kaizu K FAU - Matsumoto, Koichi AU - Matsumoto K FAU - Soma, Masayoshi AU - Soma M LA - eng PT - Journal Article DEP - 20110326 PL - Ireland TA - Diabetes Res Clin Pract JT - Diabetes research and clinical practice JID - 8508335 RN - 0 (Intercellular Signaling Peptides and Proteins) RN - 0 (Interleukin-18) RN - 0 (interleukin-18 binding protein) SB - IM MH - Adult MH - Aged MH - Albuminuria/blood MH - Diabetes Mellitus, Type 2/blood MH - Diabetic Nephropathies/*blood/physiopathology MH - Female MH - Humans MH - Intercellular Signaling Peptides and Proteins/*blood MH - Interleukin-18/*blood MH - Male MH - Middle Aged EDAT- 2011/03/29 06:00 MHDA- 2011/10/18 06:00 CRDT- 2011/03/29 06:00 PHST- 2011/01/31 00:00 [received] PHST- 2011/02/17 00:00 [revised] PHST- 2011/02/22 00:00 [accepted] PHST- 2011/03/29 06:00 [entrez] PHST- 2011/03/29 06:00 [pubmed] PHST- 2011/10/18 06:00 [medline] AID - S0168-8227(11)00110-0 [pii] AID - 10.1016/j.diabres.2011.02.028 [doi] PST - ppublish SO - Diabetes Res Clin Pract. 2011 Jun;92(3):e66-9. doi: 10.1016/j.diabres.2011.02.028. Epub 2011 Mar 26.