PMID- 21440707
OWN - NLM
STAT- MEDLINE
DCOM- 20110628
LR  - 20220411
IS  - 1532-821X (Electronic)
IS  - 0003-9993 (Linking)
VI  - 92
IP  - 4
DP  - 2011 Apr
TI  - Determining the minimal clinically important difference for the six-minute walk 
      test and the 200-meter fast-walk test during cardiac rehabilitation program in 
      coronary artery disease patients after acute coronary syndrome.
PG  - 611-9
LID - 10.1016/j.apmr.2010.11.023 [doi]
AB  - OBJECTIVE: To estimate the minimal clinically important difference (MCID) for the 
      6-minute walk test (6MWT) and the 200-m fast-walk test (FWT) in patients with 
      coronary artery disease (CAD) during a cardiac rehabilitation program. DESIGN: 
      Prospective study using distribution- and anchor-based methods. SETTING: 
      Outpatients from a cardiac rehabilitation unit. PARTICIPANTS: Stable patients 
      with CAD (N=81; 77 men; mean+/-SD age, 58.1+/-8.7y) enrolled 31+/-12.1 days after an 
      acute coronary syndrome (ACS). INTERVENTIONS: Not applicable. MAIN OUTCOME 
      MEASURES: 6MWT and 200-m FWT results before and after an 8-week cardiac 
      rehabilitation program and at the 6th and 12th sessions. Patients and 
      physiotherapists who supervised the training were asked to provide a global 
      rating of perceived change in walking ability while blinded to changes in walk 
      test performances. RESULTS: Mean change in 6MWT distance (6MWD) in patients who 
      reported no change was -6.5m versus 23.3m in those who believed their performance 
      had improved (P<.001). This result was consistent with the MCID determined by 
      using the distribution method (23m). Considering a 25-m cutoff, positive and 
      negative predictive values were 0.9 and .63, respectively. Conversely, there was 
      no difference in 200-m FWT performance between these 2 groups (0.1 vs -1.4s, 
      respectively). There was poor agreement with the physiotherapist's perceived 
      change. CONCLUSIONS: The MCID for 6MWD in patients with CAD after ACS was 25m. 
      This result will help physicians interpret 6MWD change and help researchers 
      estimate sample sizes in further studies using 6MWD as an endpoint.
CI  - Copyright (c) 2011 American Congress of Rehabilitation Medicine. Published by 
      Elsevier Inc. All rights reserved.
FAU - Gremeaux, Vincent
AU  - Gremeaux V
AD  - Pole Reeducation-Readaptation, Centre Hospitalier Universitaire de Dijon, France. 
      vincent.gremeaux@chu-dijon.fr
FAU - Troisgros, Odile
AU  - Troisgros O
FAU - Benaim, Sylvie
AU  - Benaim S
FAU - Hannequin, Armelle
AU  - Hannequin A
FAU - Laurent, Yves
AU  - Laurent Y
FAU - Casillas, Jean-Marie
AU  - Casillas JM
FAU - Benaim, Charles
AU  - Benaim C
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Arch Phys Med Rehabil
JT  - Archives of physical medicine and rehabilitation
JID - 2985158R
SB  - IM
MH  - Acute Coronary Syndrome/*rehabilitation
MH  - Coronary Artery Disease/*rehabilitation
MH  - Exercise Test/*methods
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Predictive Value of Tests
MH  - Prospective Studies
MH  - Risk Factors
MH  - Treatment Outcome
MH  - Walking/*physiology
EDAT- 2011/03/29 06:00
MHDA- 2011/06/29 06:00
CRDT- 2011/03/29 06:00
PHST- 2010/09/30 00:00 [received]
PHST- 2010/11/22 00:00 [revised]
PHST- 2010/11/22 00:00 [accepted]
PHST- 2011/03/29 06:00 [entrez]
PHST- 2011/03/29 06:00 [pubmed]
PHST- 2011/06/29 06:00 [medline]
AID - S0003-9993(10)00963-9 [pii]
AID - 10.1016/j.apmr.2010.11.023 [doi]
PST - ppublish
SO  - Arch Phys Med Rehabil. 2011 Apr;92(4):611-9. doi: 10.1016/j.apmr.2010.11.023.