PMID- 21441499
OWN - NLM
STAT- MEDLINE
DCOM- 20110803
LR  - 20151119
IS  - 1544-0737 (Electronic)
IS  - 0895-9374 (Linking)
VI  - 23
IP  - 1
DP  - 2011 Apr
TI  - Clinical markers of immunodeficiency and mechanism of immune reconstitution 
      inflammatory syndrome and highly active antiretroviral therapy on HIV: workshop 
      3A.
PG  - 165-71
LID - 10.1177/0022034511400080 [doi]
AB  - Antiretroviral therapy (ART) has improved survival and changed the disease 
      pattern of HIV infection. However, ART may cause serious side effects, such as 
      metabolic and cardiovascular complications. In addition, immune reconstitution 
      inflammatory syndrome (IRIS) is being increasingly reported in relation to ART. 
      The article presents the consensus of a workshop around 4 key issues: (1) the 
      differences in the response of adults and children to highly active 
      antiretroviral therapy, (2) the mechanism of the new HIV entry inhibitors and its 
      effect on oral markers, (3) the pathogenesis of IRIS and the contradictory 
      findings of the possible oral lesions related with IRIS, (4) and the benefits and 
      barriers associated with using ART in the developing and developed world. The 
      consensus of the workshop was that there is a need for future studies on the oral 
      manifestations of HIV in individuals treated with new ARTs-especially, children. 
      IRIS was considered a promising field for future research; as such, workshop 
      attendees recommended formulating an IRIS-oral lesions case definition and 
      following strict criteria for its diagnosis.
FAU - Ramirez-Amador, V
AU  - Ramirez-Amador V
AD  - Department of Health Sciences. Universidad Autonoma Metropolitana-Xochimilco, 
      Mexico City, Mexico.
FAU - Nittayananta, W
AU  - Nittayananta W
FAU - Magalhaes, M
AU  - Magalhaes M
FAU - Flint, S R
AU  - Flint SR
FAU - Peters, B S
AU  - Peters BS
FAU - Tappuni, A R
AU  - Tappuni AR
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Adv Dent Res
JT  - Advances in dental research
JID - 8802131
RN  - 0 (Biomarkers)
RN  - 0 (CCR5 Receptor Antagonists)
RN  - 0 (HIV Fusion Inhibitors)
MH  - Adult
MH  - Age Factors
MH  - Antiretroviral Therapy, Highly Active/*adverse effects
MH  - Biomarkers
MH  - CCR5 Receptor Antagonists
MH  - Child
MH  - *Developing Countries
MH  - Focus Groups
MH  - HIV Fusion Inhibitors/*pharmacology/therapeutic use
MH  - HIV Infections/diagnosis/*drug therapy
MH  - Humans
MH  - Immune Reconstitution Inflammatory Syndrome/*etiology/pathology
EDAT- 2011/03/29 06:00
MHDA- 2011/08/04 06:00
CRDT- 2011/03/29 06:00
PHST- 2011/03/29 06:00 [entrez]
PHST- 2011/03/29 06:00 [pubmed]
PHST- 2011/08/04 06:00 [medline]
AID - 23/1/165 [pii]
AID - 10.1177/0022034511400080 [doi]
PST - ppublish
SO  - Adv Dent Res. 2011 Apr;23(1):165-71. doi: 10.1177/0022034511400080.