PMID- 21446489 OWN - NLM STAT- MEDLINE DCOM- 20110511 LR - 20190715 IS - 1533-4880 (Print) IS - 1533-4880 (Linking) VI - 11 IP - 1 DP - 2011 Jan TI - Protein-based multi-bit biomemory device consisting of various metalloproteins on self-assembled 11-MUA layer. PG - 523-7 AB - A multi-bit biomemory device was devised by introducing 4 different metalloproteins (azurin, cytochrome c, ferredoxin, myoglobin) to an electronic device using 11-MUA (11-mercapto-undecanoic acid) as the chemical linker. The immobilization of the 4 different self-assembled protein layers on a Au substrate via 11-MUA were confirmed by Raman spectroscopy and atomic force microscopy (AFM). The redox properties of these 4 different protein layers immobilized onto Au surface were assessed by cyclic voltammetry (CV). In addition, their memory functions were verified by chronoamperometry (CA). Based on these results, we demonstrated that a multi-bit biomemory concept could be realized using various metalloproteins as active materials. FAU - Lee, Taek AU - Lee T AD - Department of Chemical and Biomolecular Engineering, Sogang University, #1 Shinsu-dong, Mapo-gu, Seoul 121-742, Republic of Korea. FAU - Min, Junhong AU - Min J FAU - Lee, Jin-Ho AU - Lee JH FAU - Choi, Jeong-Woo AU - Choi JW LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - J Nanosci Nanotechnol JT - Journal of nanoscience and nanotechnology JID - 101088195 RN - 0 (11-mercaptoundecanoic acid) RN - 0 (Bacterial Proteins) RN - 0 (Fatty Acids) RN - 0 (Fungal Proteins) RN - 0 (Metalloproteins) RN - 0 (Sulfhydryl Compounds) SB - IM MH - Animals MH - Bacterial Proteins/chemistry MH - Biosensing Techniques/methods MH - Fatty Acids/*chemistry MH - Fungal Proteins/chemistry MH - Metalloproteins/*chemistry MH - Microarray Analysis/*methods MH - Microscopy, Atomic Force MH - Nanostructures/chemistry/*ultrastructure MH - Nanotechnology/*methods MH - Spectrum Analysis, Raman MH - Sulfhydryl Compounds/*chemistry EDAT- 2011/03/31 06:00 MHDA- 2011/05/12 06:00 CRDT- 2011/03/31 06:00 PHST- 2011/03/31 06:00 [entrez] PHST- 2011/03/31 06:00 [pubmed] PHST- 2011/05/12 06:00 [medline] AID - 10.1166/jnn.2011.3272 [doi] PST - ppublish SO - J Nanosci Nanotechnol. 2011 Jan;11(1):523-7. doi: 10.1166/jnn.2011.3272.