PMID- 21448690
OWN - NLM
STAT- MEDLINE
DCOM- 20111018
LR  - 20211020
IS  - 1741-0444 (Electronic)
IS  - 0140-0118 (Linking)
VI  - 49
IP  - 8
DP  - 2011 Aug
TI  - Transesophageal left ventricular electrogram-recording and temporary pacing to 
      improve patient selection for cardiac resynchronization.
PG  - 851-8
LID - 10.1007/s11517-011-0767-6 [doi]
AB  - Cardiac resynchronization therapy (CRT) with biventricular pacing (BV) is an 
      established therapy for heart failure (HF) patients with inter- and 
      intraventricular conduction delay. The aim of this pilot study was to test the 
      feasibility of both transesophageal measurement of left ventricular (LV) 
      electrical delay and transesophageal LV pacing prior to implantation, to better 
      select patients for CRT. Esophageal TO8 Osypka catheter was perorally applied in 
      30 HF patients in position of maximum LV deflection to measure LV electrical 
      delay and to study arterial pulse pressure (PP) during transesophageal bipolar LV 
      pacing. There were 15 responders with a PP increase of a mean 65 +/- 24 mmHg to 79 
      +/- 27 mmHg (P < 0.001) and a mean LV electrical delay of 86.8 +/- 33 ms. The 15 
      non-responders with poor PP increase of a mean 63.5 +/- 23.5 mmHg to 64.1 +/- 23.9 
      mmHg (P = 0.065) had a significantly smaller LV electrical delay of 36 +/- 21 ms (P 
      < 0.001). During a 34 +/- 26 month CRT follow-up, the responders New York Heart 
      Association (NYHA) class improved from 3.1 +/- 0.35 to 2.1 +/- 0.35 (P < 0.001). 
      Determination of left ventricular electrical delay by transesophageal electrogram 
      recording and transesophageal left ventricular pacing may be additional useful 
      techniques to improve patient selection for CRT.
FAU - Heinke, Matthias
AU  - Heinke M
AD  - Division of Cardiology, Department of Internal Medicine I, Friedrich Schiller 
      University of Jena, Erlanger Allee 101, 07740 Jena, Germany. 
      matthias.heinke@med.uni-jena.de
FAU - Ismer, Bruno
AU  - Ismer B
FAU - Kuhnert, Helmut
AU  - Kuhnert H
FAU - Figulla, Hans R
AU  - Figulla HR
LA  - eng
PT  - Journal Article
DEP - 20110330
PL  - United States
TA  - Med Biol Eng Comput
JT  - Medical & biological engineering & computing
JID - 7704869
SB  - IM
MH  - Adult
MH  - Aged
MH  - Blood Pressure/physiology
MH  - Cardiac Pacing, Artificial/*methods
MH  - Cardiac Resynchronization Therapy/methods
MH  - Electrocardiography/instrumentation/methods
MH  - Feasibility Studies
MH  - Female
MH  - Heart Failure/physiopathology/*therapy
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Patient Selection
MH  - Pilot Projects
EDAT- 2011/03/31 06:00
MHDA- 2011/10/19 06:00
CRDT- 2011/03/31 06:00
PHST- 2010/12/16 00:00 [received]
PHST- 2011/03/14 00:00 [accepted]
PHST- 2011/03/31 06:00 [entrez]
PHST- 2011/03/31 06:00 [pubmed]
PHST- 2011/10/19 06:00 [medline]
AID - 10.1007/s11517-011-0767-6 [doi]
PST - ppublish
SO  - Med Biol Eng Comput. 2011 Aug;49(8):851-8. doi: 10.1007/s11517-011-0767-6. Epub 
      2011 Mar 30.