PMID- 21457147
OWN - NLM
STAT- MEDLINE
DCOM- 20111028
LR  - 20221207
IS  - 1399-0039 (Electronic)
IS  - 0001-2815 (Linking)
VI  - 78
IP  - 1
DP  - 2011 Jul
TI  - Eight new alleles found in Flanders (Belgium), including the HLA-DRB1*12:24N 
      allele.
PG  - 45-8
LID - 10.1111/j.1399-0039.2011.01660.x [doi]
AB  - Human leukocyte antigen (HLA) high-resolution matching is routinely performed in 
      the case of hematopoietic stem cell transplantation. Misdiagnosis of rare or new 
      variants will result in additional unknown mismatches that can trigger graft 
      versus host disease and/or graft failure. Using a mono allelic sequencing 
      strategy, we obtained >90% first-step sequence-based high-resolution typing 
      results, conforming to the standards set down by the European Federation for 
      Immunogenetics. During this routine analysis, eight new HLA alleles were 
      identified, including one DRB1*12 null variant, DRB1*12:24N and three other 
      coding mutants, resulting in a change of properties of the corresponding 
      antigens.
CI  - (c) 2011 John Wiley & Sons A/S.
FAU - Van Sandt, V S T
AU  - Van Sandt VS
AD  - HILA, Histocompatibility and Immunogenetic Laboratory, Red Cross Flanders, 
      Antwerpen, Belgium. vicky.vansandt@rodekruis.be
FAU - Mahieu, S
AU  - Mahieu S
FAU - Emonds, M P
AU  - Emonds MP
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20110404
PL  - England
TA  - Tissue Antigens
JT  - Tissue antigens
JID - 0331072
RN  - 0 (HLA-DR Antigens)
RN  - 0 (HLA-DRB1 Chains)
SB  - IM
MH  - Alleles
MH  - Base Sequence
MH  - Belgium
MH  - HLA-DR Antigens/*genetics
MH  - HLA-DRB1 Chains
MH  - Histocompatibility Testing
MH  - Humans
MH  - Male
MH  - White People/genetics
EDAT- 2011/04/05 06:00
MHDA- 2011/10/29 06:00
CRDT- 2011/04/05 06:00
PHST- 2011/04/05 06:00 [entrez]
PHST- 2011/04/05 06:00 [pubmed]
PHST- 2011/10/29 06:00 [medline]
AID - 10.1111/j.1399-0039.2011.01660.x [doi]
PST - ppublish
SO  - Tissue Antigens. 2011 Jul;78(1):45-8. doi: 10.1111/j.1399-0039.2011.01660.x. Epub 
      2011 Apr 4.