PMID- 21457185 OWN - NLM STAT- MEDLINE DCOM- 20110922 LR - 20240109 IS - 1600-9657 (Electronic) IS - 1600-4469 (Linking) VI - 27 IP - 3 DP - 2011 Jun TI - Short-term antimicrobial properties of mineral trioxide aggregate with incorporated silver-zeolite. PG - 189-94 LID - 10.1111/j.1600-9657.2011.00986.x [doi] AB - The purpose of this in vitro study was to determine whether adding silver-zeolite (SZ) to mineral trioxide aggregate (MTA) would enhance the antimicrobial activity of MTA against Staphylococcus aureus (ATCC #25923), Enterococcus faecalis (ATCC #29212), Escherichia coli (ATCC#25922), Pseudomonas aeruginosa (ATCC #27853), Candida albicans (ATCC #90028), Porphyromonas gingivalis (ATCC #33277), Actinomyces israelii (ATCC #12102), and Prevotella intermedia (ATCC# 15032). SZ was added at 0.2% and 2% mass fraction concentration to MTA powder. The control group was MTA powder with no SZ. The antimicrobial effect test was accomplished by placing freshly mixed MTA specimens on agar plates inoculated with microorganisms and comparing the zones of inhibition at 24, 48, and 72 h. The amounts of silver ion release from MTA specimens were measured with atomic absorption spectrophotometry at 10-min, 24-, 48-, and 72-h periods. The pH of MTA specimens was measured with a pH meter at 10-min, 24-, 48-, and 72-h periods. MTA with 2% and 0.2% SZ specimens showed inhibitory effects on some microorganisms at all time periods, whereas no antimicrobial activity showed for P. intermedia and A. israelii. MTA without SZ inhibited C. albicans, E. Coli, and P. intermedia. The highest silver release was detected in 2% SZ MTA at 24 h. The incorporation of SZ may enhance the antimicrobial activity of MTA. CI - (c) 2011 John Wiley & Sons A/S. FAU - Odabas, Mesut E AU - Odabas ME AD - Departments of Pediatric Dentistry Microbiology, Faculty of Dentistry, University of Gazi Department of Chemical Engineering, Faculty of Engineering, University of Middle East Technical, Ankara, Turkey. mesut@gazi.edu.tr FAU - Cinar, Cagdas AU - Cinar C FAU - Akca, Gulcin AU - Akca G FAU - Araz, Ibrahim AU - Araz I FAU - Ulusu, Tezer AU - Ulusu T FAU - Yucel, Hayrettin AU - Yucel H LA - eng PT - Comparative Study PT - Journal Article DEP - 20110404 PL - Denmark TA - Dent Traumatol JT - Dental traumatology : official publication of International Association for Dental Traumatology JID - 101091305 RN - 0 (Aluminum Compounds) RN - 0 (Anti-Infective Agents) RN - 0 (Calcium Compounds) RN - 0 (Culture Media) RN - 0 (Drug Combinations) RN - 0 (Oxides) RN - 0 (Root Canal Filling Materials) RN - 0 (Silicates) RN - 0 (mineral trioxide aggregate) RN - 1318-02-1 (Zeolites) RN - 3M4G523W1G (Silver) MH - Actinomyces/drug effects MH - Aluminum Compounds/chemistry/*pharmacology MH - Anti-Infective Agents/*pharmacology MH - Calcium Compounds/chemistry/*pharmacology MH - Candida albicans/drug effects MH - Culture Media MH - Diffusion MH - Drug Combinations MH - Enterococcus faecalis/drug effects MH - Escherichia coli/drug effects MH - Humans MH - Hydrogen-Ion Concentration MH - Materials Testing MH - Oxides/chemistry/*pharmacology MH - Porphyromonas gingivalis/drug effects MH - Prevotella intermedia/drug effects MH - Pseudomonas aeruginosa/drug effects MH - Root Canal Filling Materials/chemistry/*pharmacology MH - Silicates/chemistry/*pharmacology MH - Silver/chemistry/*pharmacology MH - Spectrophotometry, Atomic MH - Staphylococcus aureus/drug effects MH - Time Factors MH - Zeolites/*pharmacology EDAT- 2011/04/05 06:00 MHDA- 2011/09/23 06:00 CRDT- 2011/04/05 06:00 PHST- 2011/04/05 06:00 [entrez] PHST- 2011/04/05 06:00 [pubmed] PHST- 2011/09/23 06:00 [medline] AID - 10.1111/j.1600-9657.2011.00986.x [doi] PST - ppublish SO - Dent Traumatol. 2011 Jun;27(3):189-94. doi: 10.1111/j.1600-9657.2011.00986.x. Epub 2011 Apr 4.