PMID- 21459456 OWN - NLM STAT- MEDLINE DCOM- 20111108 LR - 20110919 IS - 0165-1781 (Print) IS - 0165-1781 (Linking) VI - 189 IP - 2 DP - 2011 Sep 30 TI - Study of HLA Class I gene in Indian schizophrenic patients of Siliguri, West Bengal. PG - 215-9 LID - 10.1016/j.psychres.2011.03.010 [doi] AB - The authors studied the prevalence of the human leukocyte antigen (HLA) Class I gene in 136 (85 male, 51 female) India-born schizophrenia patients residing in and around the Siliguri subdivision of West Bengal by the PCR-SSP method. The control group consisted of 150 age- and sex-matched healthy individuals from the same ethnic group as the patients. Increased frequency of HLA A*03 as well as decreased frequencies of HLA A*31 and HLA B*51, was noted. The study suggests the possible existence of a susceptibility locus for schizophrenia within the HLA region. CI - Copyright (c) 2011 Elsevier Ireland Ltd. All rights reserved. FAU - Singh, Bisu AU - Singh B AD - Department of Zoology, University of North Bengal, Siliguri, West Bengal, India. FAU - Bera, Nirmal Kumar AU - Bera NK FAU - De, Santanu AU - De S FAU - Nayak, Chittaranjan AU - Nayak C FAU - Chaudhuri, Tapas Kumar AU - Chaudhuri TK LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20110402 PL - Ireland TA - Psychiatry Res JT - Psychiatry research JID - 7911385 RN - 0 (HLA Antigens) RN - 0 (Histocompatibility Antigens Class I) SB - IM MH - Adult MH - Case-Control Studies MH - Female MH - Gene Frequency MH - Genes, MHC Class I/*genetics MH - *Genetic Predisposition to Disease MH - Genetic Testing/methods MH - Genotype MH - HLA Antigens MH - Histocompatibility Antigens Class I/*genetics MH - Humans MH - India/epidemiology/ethnology MH - Male MH - Middle Aged MH - Young Adult EDAT- 2011/04/05 06:00 MHDA- 2011/11/09 06:00 CRDT- 2011/04/05 06:00 PHST- 2010/07/31 00:00 [received] PHST- 2011/03/10 00:00 [revised] PHST- 2011/03/11 00:00 [accepted] PHST- 2011/04/05 06:00 [entrez] PHST- 2011/04/05 06:00 [pubmed] PHST- 2011/11/09 06:00 [medline] AID - S0165-1781(11)00233-2 [pii] AID - 10.1016/j.psychres.2011.03.010 [doi] PST - ppublish SO - Psychiatry Res. 2011 Sep 30;189(2):215-9. doi: 10.1016/j.psychres.2011.03.010. Epub 2011 Apr 2.