PMID- 21468372
OWN - NLM
STAT- MEDLINE
DCOM- 20110526
LR  - 20220410
IS  - 0300-0729 (Print)
IS  - 0300-0729 (Linking)
VI  - 49
IP  - 1
DP  - 2011 Mar
TI  - Minimal clinically important differences in nasal peak inspiratory flow.
PG  - 37-40
LID - 10.4193/Rhino10.097 [doi]
AB  - INTRODUCTION: Acoustic Rhinometry, Rhinomanometry, Nasal Spirometry and Nasal 
      Peak Inspiratory flow (NPIF) all measure subtly different constructs of nasal 
      function. All have limitations but NPIF is simple and quick to integrate into 
      clinical practice. The minimum clinically important difference (MCID) for an 
      outcome measure is an estimate of the smallest change that is experienced by a 
      patient or group as being significant. Studies, particularly with large samples, 
      may generate results that while statistically significant, have limited clinical 
      effect. Defining MCID allows an assessment of the clinical impact of an 
      intervention. This study defines the MCID for NPIF. METHODS: Prospective study of 
      patients from a tertiary clinic undergoing open septorhinoplasty. Nasal 
      obstruction scores and NPIF were recorded before and after surgery. Global 
      function and nasal obstruction scores were used to assess subjective change. 
      Statistical based and patient anchored techniques were used to define MCID. 
      RESULTS: 51 patients with a mean age 36 +- 13 yrs (75% female) were recruited. 
      All had open rhinoplasty, septal reconstruction, spreader grafts and turbinate 
      reduction. Baseline NPIF was 101 +- 35 L/min. The statistically derived MCID 
      (half standard deviation) was 18 L/min, the patient anchored approaches were 20 
      L/min and 20-25 L/min. DISCUSSION: Although NPIF is effort dependant with the 
      potential for poor test-retest reliability, it is simple, quick and a reliable 
      technique can be quickly learnt. An MCID of 20L/min is recommended when NPIF is 
      used as an outcome tool. Understanding the MCID is critical for assessing the 
      impact of nasal surgery.
FAU - Timperley, Daniel
AU  - Timperley D
AD  - Department of Otolaryngology / Skull Base Surgery, St. Vincent;s Hospital, 
      Victoria St, Darlinghurst, Sydney NSW 2010, Australia. daniel.timperley@gmail.com
FAU - Srubisky, Aviva
AU  - Srubisky A
FAU - Stow, Nicholas
AU  - Stow N
FAU - Marcells, George N
AU  - Marcells GN
FAU - Harvey, Richard J
AU  - Harvey RJ
LA  - eng
PT  - Journal Article
PL  - Netherlands
TA  - Rhinology
JT  - Rhinology
JID - 0347242
SB  - IM
MH  - Adult
MH  - Female
MH  - Humans
MH  - Male
MH  - Nasal Obstruction/*physiopathology
MH  - Nose/*physiopathology
MH  - Prospective Studies
MH  - Respiratory Function Tests
MH  - Rhinoplasty
EDAT- 2011/04/07 06:00
MHDA- 2011/05/27 06:00
CRDT- 2011/04/07 06:00
PHST- 2011/04/07 06:00 [entrez]
PHST- 2011/04/07 06:00 [pubmed]
PHST- 2011/05/27 06:00 [medline]
AID - 10.4193/Rhino10.097 [doi]
PST - ppublish
SO  - Rhinology. 2011 Mar;49(1):37-40. doi: 10.4193/Rhino10.097.