PMID- 21468743
OWN - NLM
STAT- MEDLINE
DCOM- 20111004
LR  - 20211020
IS  - 1432-1041 (Electronic)
IS  - 0031-6970 (Linking)
VI  - 67
IP  - 7
DP  - 2011 Jul
TI  - Prevention and current onset delay approaches of type 2 diabetes mellitus (T2DM).
PG  - 653-61
LID - 10.1007/s00228-011-1038-z [doi]
AB  - The urgent need to treat type 2 diabetes mellitus (T2DM), which is currently 
      reaching epidemic proportions, has been a major focus of healthcare systems and 
      policy makers worldwide. Pharmacological treatment and lifestyle interventions 
      together with the control of cardiovascular risk factors are the main strategies 
      to prevent or delay the onset of T2DM. The present review discusses the state of 
      the art knowledge of effective therapeutic approaches (metformin, 
      thiazolidinediones, nateglinides, alpha-glucosidase inhibitors, incretin-based and 
      angiotensin-based therapies, weight reducers, statins, fibric acid derivatives), 
      including surgery, and identifies the major lifestyle changes for specific target 
      groups.
FAU - Souto, Selma B
AU  - Souto SB
AD  - Department of Endocrinology, Hospital de Sao Joao, Alameda Prof. Hernani 
      Monteiro, 4200-319, Porto, Portugal. sbsouto.md@gmail.com
FAU - Souto, Eliana B
AU  - Souto EB
FAU - Braga, Daniel C
AU  - Braga DC
FAU - Medina, Jose L
AU  - Medina JL
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20110406
PL  - Germany
TA  - Eur J Clin Pharmacol
JT  - European journal of clinical pharmacology
JID - 1256165
RN  - 0 (Hypoglycemic Agents)
SB  - IM
MH  - Diabetes Mellitus, Type 2/*prevention & control
MH  - Humans
MH  - Hypoglycemic Agents/therapeutic use
EDAT- 2011/04/07 06:00
MHDA- 2011/10/05 06:00
CRDT- 2011/04/07 06:00
PHST- 2010/12/24 00:00 [received]
PHST- 2011/03/15 00:00 [accepted]
PHST- 2011/04/07 06:00 [entrez]
PHST- 2011/04/07 06:00 [pubmed]
PHST- 2011/10/05 06:00 [medline]
AID - 10.1007/s00228-011-1038-z [doi]
PST - ppublish
SO  - Eur J Clin Pharmacol. 2011 Jul;67(7):653-61. doi: 10.1007/s00228-011-1038-z. Epub 
      2011 Apr 6.