PMID- 21468747
OWN - NLM
STAT- MEDLINE
DCOM- 20120604
LR  - 20211020
IS  - 1439-6327 (Electronic)
IS  - 1439-6319 (Linking)
VI  - 111
IP  - 12
DP  - 2011 Dec
TI  - Carbohydrate intake reduces fat oxidation during exercise in obese boys.
PG  - 3135-41
LID - 10.1007/s00421-011-1940-1 [doi]
AB  - The recent surge in childhood obesity has renewed interest in studying exercise 
      as a therapeutic means of metabolizing fat. However, carbohydrate (CHO) intake 
      attenuates whole body fat oxidation during exercise in healthy children and may 
      suppress fat metabolism in obese youth. To determine the impact of CHO intake on 
      substrate utilization during submaximal exercise in obese boys, seven obese boys 
      (mean age: 11.4 +/- 1.0 year; % body fat: 35.8 +/- 3.9%) performed 60 min of exercise 
      at an intensity that approximated maximal fat oxidation. A CHO drink (CARB) or a 
      placebo drink (CONT) was consumed in a double-blinded, counterbalanced manner. 
      Rates of total fat, total CHO, and exogenous CHO (CHO(exo)) oxidation were 
      calculated for the last 20 min of exercise. During CONT, fat oxidation rate was 
      3.9 +/- 2.4 mg x kg fat-free mass (FFM)(-1 )x min(-1), representing 43.1 +/- 22.9% of 
      total energy expenditure (EE). During CARB, fat oxidation was lowered (p = 0.02) 
      to 1.7 +/- 0.6 mg x kg FFM(-1 )x min(-1), contributing to 19.8 +/- 4.9% EE. Total CHO 
      oxidation rate was 17.2 +/- 3.1 mg x kg FFM(-1 )x min(-1) and 13.2 +/- 6.1 mg x kg 
      FFM(-1) x min(-1) during CARB and CONT, respectively (p = 0.06). In CARB, 
      CHO(exo) oxidation contributed to 23.3 +/- 4.2% of total EE. CHO intake markedly 
      suppresses fat oxidation during exercise in obese boys.
FAU - Chu, Lisa
AU  - Chu L
AD  - Children's Exercise and Nutrition Centre, McMaster University, Children's 
      Hospital, Chedoke Hospital, Evel Bldg, Room 469, Sanatorium Road, P.O. Box 2000, 
      Hamilton, ON, L8N 3Z5, Canada.
FAU - Riddell, Michael C
AU  - Riddell MC
FAU - Takken, Tim
AU  - Takken T
FAU - Timmons, Brian W
AU  - Timmons BW
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20110406
PL  - Germany
TA  - Eur J Appl Physiol
JT  - European journal of applied physiology
JID - 100954790
RN  - 0 (Dietary Carbohydrates)
SB  - IM
MH  - Adipose Tissue/*metabolism
MH  - Carbohydrate Metabolism/physiology
MH  - Child
MH  - Dietary Carbohydrates/*administration & dosage/metabolism
MH  - Double-Blind Method
MH  - Energy Intake/physiology
MH  - Energy Metabolism/physiology
MH  - Exercise/*physiology
MH  - Heart Rate/physiology
MH  - Humans
MH  - Lipid Metabolism/*physiology
MH  - Male
MH  - Obesity/*metabolism
MH  - Oxidation-Reduction
MH  - Oxygen Consumption/physiology
EDAT- 2011/04/07 06:00
MHDA- 2012/06/05 06:00
CRDT- 2011/04/07 06:00
PHST- 2010/09/18 00:00 [received]
PHST- 2011/03/21 00:00 [accepted]
PHST- 2011/04/07 06:00 [entrez]
PHST- 2011/04/07 06:00 [pubmed]
PHST- 2012/06/05 06:00 [medline]
AID - 10.1007/s00421-011-1940-1 [doi]
PST - ppublish
SO  - Eur J Appl Physiol. 2011 Dec;111(12):3135-41. doi: 10.1007/s00421-011-1940-1. 
      Epub 2011 Apr 6.