PMID- 21479791
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20110927
LR  - 20160512
IS  - 1618-2650 (Electronic)
IS  - 1618-2642 (Linking)
VI  - 400
IP  - 9
DP  - 2011 Jul
TI  - Analytical characteristics and determination of major novel brominated flame 
      retardants (NBFRs) in indoor dust.
PG  - 3073-83
LID - 10.1007/s00216-011-4966-7 [doi]
AB  - A new method was developed and optimized for the detection of major "novel" 
      brominated flame retardants (NBFRs), which included decabromodiphenyl ethane 
      (DBDPE), 1,2-bis(2,4,6-tribromophenoxy) ethane (BTBPE), tetrabromobisphenol 
      A-bis(2,3-dibromopropylether) (TBBPA-DBPE), 
      2-ethylhexyl-2,3,4,5-tetrabromobenzoate (TBB), 
      bis(2-ethylhexyl)-3,4,5,6-tetrabromophthalate (TBPH) and 
      hexachlorocyclopentadienyl-dibromocyclooctane (HCDBCO). Several solid phase 
      sorbents were tested, and finally, a two-step cleanup procedure was established. 
      The first step on activated silica was used to fractionate the dust extracts, 
      while the second step on acidified silica (silica gel impregnated with sulphuric 
      acid 44% w/w) and on Florisil((R)), respectively, was essential for advanced 
      cleanup. High recoveries for NBFRs (range, 75-94%) were achieved. Analysis was 
      performed by gas chromatography coupled with mass spectrometry in electron 
      capture negative ionization using a DB-5ms (15 m x 0.25 mm x 0.1 mum) capillary 
      column. Quantification of DBDPE, BTBPE and TBBPA-DBPE was based on ion m/z 79, 
      while characteristic ions were used for quantification of TBB (m/z 359), HCDBCO 
      (m/z 310) and TBPH (m/z 384). The method provided good repeatability; within- and 
      between-day precision were </=14% for all NBFRs. Method limits of quantification 
      ranged between 1 and 20 ng g(-1); dust and NBFRs were not detected in blanks. The 
      method was further applied to indoor dust (n = 21) collected from e-waste 
      facilities in Thailand. Except for HCDBCO, all NBFRs were detected in the e-waste 
      dust with concentrations up to 44,000 and 22,600 ng g(-1) DBDPE and BTBPE, 
      respectively. The dust profile was dominated by DBDPE (50%) > BTBPE (45%) > 
      TBBPA-DBPE (3%) > TBPH (1.9%) > TBB (0.1%). Significant correlations (p < 0.05) 
      were found between the concentrations of BTBPE and BDE 183 or BDE 197 on the one 
      hand, between TBPH and BDE 47 or BDE 99, and between DBDPE and BDE 209, on the 
      other hand. Concentrations of TBB were not positively correlated with TBPH, which 
      suggests different emission sources.
FAU - Ali, Nadeem
AU  - Ali N
AD  - Toxicological Centre, University of Antwerp, Wilrijk-Antwerp, Belgium.
FAU - Harrad, Stuart
AU  - Harrad S
FAU - Muenhor, Dudsadee
AU  - Muenhor D
FAU - Neels, Hugo
AU  - Neels H
FAU - Covaci, Adrian
AU  - Covaci A
LA  - eng
PT  - Journal Article
DEP - 20110410
PL  - Germany
TA  - Anal Bioanal Chem
JT  - Analytical and bioanalytical chemistry
JID - 101134327
EDAT- 2011/04/12 06:00
MHDA- 2011/04/12 06:01
CRDT- 2011/04/12 06:00
PHST- 2011/01/01 00:00 [received]
PHST- 2011/03/28 00:00 [accepted]
PHST- 2011/03/23 00:00 [revised]
PHST- 2011/04/12 06:00 [entrez]
PHST- 2011/04/12 06:00 [pubmed]
PHST- 2011/04/12 06:01 [medline]
AID - 10.1007/s00216-011-4966-7 [doi]
PST - ppublish
SO  - Anal Bioanal Chem. 2011 Jul;400(9):3073-83. doi: 10.1007/s00216-011-4966-7. Epub 
      2011 Apr 10.