PMID- 21480953
OWN - NLM
STAT- MEDLINE
DCOM- 20110628
LR  - 20211020
IS  - 1365-2125 (Electronic)
IS  - 0306-5251 (Print)
IS  - 0306-5251 (Linking)
VI  - 71
IP  - 5
DP  - 2011 May
TI  - Outcomes of a decision support prompt in community pharmacy-dispensing software 
      to promote step-down of proton pump inhibitor therapy.
PG  - 780-4
LID - 10.1111/j.1365-2125.2010.03890.x [doi]
AB  - AIM: To evaluate the effect of a computerized decision support prompt regarding 
      high-dose proton pump inhibitor (PPI) therapy on prescribing and medication 
      costs. METHODS: A prompt activated on dispensing high-dose esomeprazole or 
      pantoprazole was implemented in 73 of 185 pharmacies. Anonymized prescription 
      data and a patient survey were used to determine changes in prescribing and 
      associated medication costs. RESULTS: The pharmacist-recorded PPI intervention 
      rate per 100 high-dose PPI prescriptions was 1.67 for the PPI prompt group and 
      0.17 for the control group (P < 0.001). During the first 28 days of the trial, 
      196 interventions resulted in 34 instances of PPI step-down, with 28 of these 
      occurring in PPI prompt pharmacies. Cost savings attributable to the prompt were 
      AUD 7.98 ( pound4.95) per month per PPI prompt pharmacy compared with AUD 1.05 ( pound0.65) 
      per control pharmacy. CONCLUSION: The use of electronic decision support prompts 
      in community pharmacy practice can promote the quality use of medicines.
CI  - (c) 2011 The Authors. British Journal of Clinical Pharmacology (c) 2011 The British 
      Pharmacological Society.
FAU - Curtain, Colin
AU  - Curtain C
AD  - Unit for Medication Outcomes Research and Education, School of Pharmacy, 
      University of Tasmania, Hobart, Tasmania, Australia. colin.curtain@utas.edu.au
FAU - Peterson, Gregory M
AU  - Peterson GM
FAU - Tenni, Peter
AU  - Tenni P
FAU - Bindoff, Ivan K
AU  - Bindoff IK
FAU - Williams, Mackenzie
AU  - Williams M
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
PT  - Randomized Controlled Trial
PL  - England
TA  - Br J Clin Pharmacol
JT  - British journal of clinical pharmacology
JID - 7503323
RN  - 0 (Proton Pump Inhibitors)
SB  - IM
MH  - Australia
MH  - *Community Pharmacy Services/economics
MH  - *Decision Support Techniques
MH  - Drug Costs/statistics & numerical data
MH  - Drug Prescriptions/economics/standards/statistics & numerical data
MH  - Drug Therapy, Computer-Assisted/economics/*methods
MH  - Humans
MH  - Outcome Assessment, Health Care
MH  - Proton Pump Inhibitors/*administration & dosage/economics/therapeutic use
MH  - Software
PMC - PMC3093084
EDAT- 2011/04/13 06:00
MHDA- 2011/06/29 06:00
PMCR- 2012/05/01
CRDT- 2011/04/13 06:00
PHST- 2011/04/13 06:00 [entrez]
PHST- 2011/04/13 06:00 [pubmed]
PHST- 2011/06/29 06:00 [medline]
PHST- 2012/05/01 00:00 [pmc-release]
AID - 10.1111/j.1365-2125.2010.03890.x [doi]
PST - ppublish
SO  - Br J Clin Pharmacol. 2011 May;71(5):780-4. doi: 10.1111/j.1365-2125.2010.03890.x.