PMID- 21498101
OWN - NLM
STAT- MEDLINE
DCOM- 20110808
LR  - 20220331
IS  - 1532-2750 (Electronic)
IS  - 1098-612X (Linking)
VI  - 13
IP  - 6
DP  - 2011 Jun
TI  - Cyclic estrous-like behavior in a spayed cat associated with excessive 
      sex-hormone production by an adrenocortical carcinoma.
PG  - 473-8
LID - 10.1016/j.jfms.2011.02.002 [doi]
AB  - A 15-year-old, spayed female domestic shorthair cat was evaluated for 1-year 
      duration of cyclic intermittent estrous behavior. Diagnostic testing performed 
      before referral, including baseline progesterone concentration, human chorionic 
      gonadotropin (hCG) hormone stimulation test and surgical exploratory laparotomy, 
      had remained inconclusive for a remnant ovary. Evaluation of sex hormones before 
      and after adrenocorticotropic hormone (ACTH) administration revealed increased 
      basal concentrations of androstenedione, estradiol, progesterone, and 
      17alpha-hydroxyprogesterone and normal ACTH-stimulated hormone concentrations. 
      Enlargement of the right adrenal gland was identified by abdominal ultrasound. 
      The cat underwent an adrenalectomy and histopathology of the excised adrenal 
      gland was consistent with an adrenocortical carcinoma. Clinical signs resolved 
      immediately following surgery, and most hormone concentrations declined to within 
      or below the reference interval (RI) by 2 months after surgery.
CI  - Copyright (c) 2011 ISFM and AAFP. Published by Elsevier Ltd. All rights reserved.
FAU - Meler, Erika N
AU  - Meler EN
AD  - Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Purdue 
      University, West-Lafayette, IN 47907, USA.
FAU - Scott-Moncrieff, J Catharine
AU  - Scott-Moncrieff JC
FAU - Peter, Augustine T
AU  - Peter AT
FAU - Bennett, Sara
AU  - Bennett S
FAU - Ramos-Vara, Jose
AU  - Ramos-Vara J
FAU - Salisbury, S Kathleen
AU  - Salisbury SK
FAU - Naughton, James F
AU  - Naughton JF
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20110416
PL  - England
TA  - J Feline Med Surg
JT  - Journal of feline medicine and surgery
JID - 100897329
RN  - 0 (Gonadal Steroid Hormones)
RN  - 409J2J96VR (Androstenedione)
RN  - 4G7DS2Q64Y (Progesterone)
RN  - 4TI98Z838E (Estradiol)
RN  - 68-96-2 (17-alpha-Hydroxyprogesterone)
SB  - IM
MH  - 17-alpha-Hydroxyprogesterone/blood
MH  - Adrenal Cortex Neoplasms/blood/surgery/*veterinary
MH  - Adrenocortical Carcinoma/blood/surgery/*veterinary
MH  - Androstenedione/blood
MH  - Animals
MH  - Cat Diseases/*blood/surgery
MH  - Cats
MH  - Estradiol/blood
MH  - Estrous Cycle/*blood
MH  - Female
MH  - Gonadal Steroid Hormones/*blood
MH  - Progesterone/blood
MH  - Treatment Outcome
EDAT- 2011/04/19 06:00
MHDA- 2011/08/09 06:00
CRDT- 2011/04/19 06:00
PHST- 2011/02/14 00:00 [accepted]
PHST- 2011/04/19 06:00 [entrez]
PHST- 2011/04/19 06:00 [pubmed]
PHST- 2011/08/09 06:00 [medline]
AID - S1098-612X(11)00060-X [pii]
AID - 10.1016/j.jfms.2011.02.002 [doi]
PST - ppublish
SO  - J Feline Med Surg. 2011 Jun;13(6):473-8. doi: 10.1016/j.jfms.2011.02.002. Epub 
      2011 Apr 16.