PMID- 21498280 OWN - NLM STAT- MEDLINE DCOM- 20110811 LR - 20161125 IS - 1600-0455 (Electronic) IS - 0284-1851 (Linking) VI - 52 IP - 5 DP - 2011 Jun 1 TI - The optimal contrast media policy in CT of the liver. Part II: Clinical protocols. PG - 473-80 LID - 10.1258/ar.2011.100500 [doi] AB - The advent of multidetector computed tomography (MDCT) revolutionized abdominal imaging. In particular, the definitive assessment of CT injection protocols, for the evaluation of the liver parenchyma, is still a critical issue for radiologists. Over the last years, this feature encouraged several authors to address their efforts to find the most accurate delay between the contrast medium injection and the effective scan-start, for the identification and characterization of liver lesions. Technological developments of the present century such as number of slices, submillimetric collimation, and the use of multiple dynamic post-contrast phases per single examination, may all contribute to increase the radiation exposure of single patients. The aim of this review is to propose liver imaging protocols, taking into consideration different clinical needs such as patients with chronic liver disease, healthy patients with focal liver lesion, and oncological patients to minimize radiation exposure. Finally, two recent innovations in MDCT which illustrate the potential application of multi-energy computed tomography (MECT) and perfusion computed tomography (CTp) when evaluating liver parenchyma will be discussed in a short closing paragraph. FAU - Rengo, Marco AU - Rengo M AD - Department of Radiological, Oncological and Pathological Sciences, University of Rome Sapienza, Italy. FAU - Bellini, Davide AU - Bellini D FAU - De Cecco, Carlo N AU - De Cecco CN FAU - Osimani, Marcello AU - Osimani M FAU - Vecchietti, Fabrizio AU - Vecchietti F FAU - Caruso, Damiano AU - Caruso D FAU - Maceroni, Marco M AU - Maceroni MM FAU - Lucchesi, Paola AU - Lucchesi P FAU - Iafrate, Franco AU - Iafrate F FAU - Palombo, Erica AU - Palombo E FAU - Paolantonio, Pasquale AU - Paolantonio P FAU - Ferrari, Riccardo AU - Ferrari R FAU - Laghi, Andrea AU - Laghi A LA - eng PT - Journal Article PT - Review DEP - 20110328 PL - England TA - Acta Radiol JT - Acta radiologica (Stockholm, Sweden : 1987) JID - 8706123 RN - 0 (Contrast Media) SB - IM MH - *Clinical Protocols MH - *Contrast Media/administration & dosage/pharmacokinetics MH - Humans MH - Liver Diseases/*diagnostic imaging MH - Radiation Dosage MH - Radiation Protection MH - Radiographic Image Enhancement/methods MH - Radiography, Abdominal/*methods/trends MH - Tomography, X-Ray Computed/*methods/trends EDAT- 2011/04/19 06:00 MHDA- 2011/08/13 06:00 CRDT- 2011/04/19 06:00 PHST- 2011/04/19 06:00 [entrez] PHST- 2011/04/19 06:00 [pubmed] PHST- 2011/08/13 06:00 [medline] AID - ar.2011.100500 [pii] AID - 10.1258/ar.2011.100500 [doi] PST - ppublish SO - Acta Radiol. 2011 Jun 1;52(5):473-80. doi: 10.1258/ar.2011.100500. Epub 2011 Mar 28.