PMID- 21498943
OWN - NLM
STAT- MEDLINE
DCOM- 20110829
LR  - 20190606
IS  - 1349-7235 (Electronic)
IS  - 0918-2918 (Linking)
VI  - 50
IP  - 8
DP  - 2011
TI  - Fulminant myelopathy following neurogenic proximal weakness associated with human 
      T-cell lymphotropic virus type I infection.
PG  - 919-24
AB  - We report a patient with human T-cell lymphotropic virus type I (HTLV-I) 
      infection, who presented with proximal extremity neurogenic muscular weakness 
      followed by fulminant myelopathy, but with no upper motor symptoms. The symptoms 
      were inconsistent with the World Health Organization or El Escorial criteria for 
      HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP) or 
      amyotrophic lateral sclerosis (ALS). This case indicates that fulminant 
      myelopathy without upper motor neuronal symptoms may occur long after the onset 
      of HTLV-I-associated neurogenic proximal muscular weakness. Additionally, we 
      report that treatment with high-dose steroid pulse therapy partially improves 
      symptoms of lightning pain and sensory disturbance.
FAU - Yamashita, Satoshi
AU  - Yamashita S
AD  - Department of Neurology, Faculty of Life Sciences, Kumamoto University, Japan. 
      y-stsh@kumamoto-u.ac.jp
FAU - Ueda, Akihiko
AU  - Ueda A
FAU - Hirahara, Tomoo
AU  - Hirahara T
FAU - Kimura, En
AU  - Kimura E
FAU - Hirano, Teruyuki
AU  - Hirano T
FAU - Uchino, Makoto
AU  - Uchino M
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20110415
PL  - Japan
TA  - Intern Med
JT  - Internal medicine (Tokyo, Japan)
JID - 9204241
RN  - 0 (Glucocorticoids)
RN  - 9PHQ9Y1OLM (Prednisolone)
SB  - IM
MH  - Aged
MH  - Glucocorticoids/administration & dosage
MH  - Humans
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - Muscle Weakness/pathology/physiopathology
MH  - Muscular Atrophy/pathology/physiopathology
MH  - Paraparesis, Tropical Spastic/*diagnosis/drug therapy/pathology/physiopathology
MH  - Prednisolone/administration & dosage
MH  - Time Factors
EDAT- 2011/04/19 06:00
MHDA- 2011/08/30 06:00
CRDT- 2011/04/19 06:00
PHST- 2011/04/19 06:00 [entrez]
PHST- 2011/04/19 06:00 [pubmed]
PHST- 2011/08/30 06:00 [medline]
AID - JST.JSTAGE/internalmedicine/50.4647 [pii]
AID - 10.2169/internalmedicine.50.4647 [doi]
PST - ppublish
SO  - Intern Med. 2011;50(8):919-24. doi: 10.2169/internalmedicine.50.4647. Epub 2011 
      Apr 15.