PMID- 21502243
OWN - NLM
STAT- MEDLINE
DCOM- 20110607
LR  - 20181201
IS  - 1098-4275 (Electronic)
IS  - 0031-4005 (Linking)
VI  - 127 Suppl 1
DP  - 2011 May
TI  - Internet-based reporting to the vaccine adverse event reporting system: a more 
      timely and complete way for providers to support vaccine safety.
PG  - S39-44
LID - 10.1542/peds.2010-1722G [doi]
AB  - BACKGROUND: On March 22, 2002, Internet-based reports (IBRs) were added to the 
      Vaccine Adverse Event Reporting System (VAERS) to allow rapid, expedited 
      reporting of adverse events (AEs) in anticipation of wider use of 
      counter-bioterrorism vaccines such as those against smallpox and anthrax. 
      OBJECTIVES: To evaluate the impact of IBRs on the timeliness and completeness of 
      vaccine AE reporting. METHODS: To evaluate timeliness and completeness, we 
      compared the proportions of IBRs with non-Internet-based reports (NIBRs). Report 
      interval was analyzed for timeliness and age at vaccination, birth date, and 
      onset date for report completeness. To evaluate the impact of the smallpox 
      vaccination program, we compared smallpox vaccine reports separately. Because 
      influenza vaccine is the most widely used vaccine in adults each year, we 
      compared influenza vaccine reports separately. RESULTS: During the study period, 
      VAERS received 54 364 NIBRs (85.8%) and 9008 IBRs (14.2%). Sixteen percent (1455) 
      of IBRs followed smallpox vaccination. Overall, for all vaccines and for smallpox 
      vaccine alone, IBRs had a greater proportion of completeness and a shorter report 
      interval. The proportion of most frequently reported AEs did not differ between 
      IBRs and NIBRs. A higher proportion of adults (18-64 years old) who received 
      influenza vaccine chose to complete an IBR (62% vs 48%). CONCLUSIONS: The 
      improved timeliness and completeness of IBRs allow VAERS to more rapidly detect 
      new or rare vaccine AEs. This important advantage is critical in times of 
      increased public concern about vaccine safety. Clinical vaccine providers should 
      be aware of VAERS and use IBRs whenever feasible to report vaccine AEs.
FAU - Haber, Penina
AU  - Haber P
AD  - Immunization Safety Office, Division of Healthcare Quality Promotion, Centers for 
      Disease Control and Prevention, Mail Stop D-26, 1600 Clifton Rd, Atlanta, GA 
      30333, USA. phaber@cdc.gov
FAU - Iskander, John
AU  - Iskander J
FAU - Walton, Kimp
AU  - Walton K
FAU - Campbell, Scott R
AU  - Campbell SR
FAU - Kohl, Katrin S
AU  - Kohl KS
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20110418
PL  - United States
TA  - Pediatrics
JT  - Pediatrics
JID - 0376422
RN  - 0 (Vaccines)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Adverse Drug Reaction Reporting Systems/*statistics & numerical data
MH  - Age Factors
MH  - Child
MH  - Child, Preschool
MH  - Confidence Intervals
MH  - Databases, Factual
MH  - Drug-Related Side Effects and Adverse Reactions
MH  - Humans
MH  - Immunization Programs/organization & administration
MH  - Infant
MH  - Internet/*statistics & numerical data
MH  - Middle Aged
MH  - Retrospective Studies
MH  - Time Factors
MH  - United States
MH  - Vaccination/adverse effects/*statistics & numerical data
MH  - Vaccines/administration & dosage/*adverse effects
MH  - Young Adult
EDAT- 2011/04/20 06:00
MHDA- 2011/06/08 06:00
CRDT- 2011/04/20 06:00
PHST- 2011/04/20 06:00 [entrez]
PHST- 2011/04/20 06:00 [pubmed]
PHST- 2011/06/08 06:00 [medline]
AID - peds.2010-1722G [pii]
AID - 10.1542/peds.2010-1722G [doi]
PST - ppublish
SO  - Pediatrics. 2011 May;127 Suppl 1:S39-44. doi: 10.1542/peds.2010-1722G. Epub 2011 
      Apr 18.