PMID- 21503009
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20151105
LR  - 20200414
IS  - 1110-0362 (Print)
IS  - 1110-0362 (Linking)
VI  - 22
IP  - 1
DP  - 2010 Mar
TI  - Bronchoplasty for primary broncho-pulmonary tumors.
PG  - 73-8
AB  - BACKGROUND: Parenchyma-sparing procedures are widely used in patients with 
      low-grade malignancies of the airway when anatomically suited lesions exist. This 
      study was conducted to evaluate the short-term and the long-term results of 
      bronchoplastic procedures for patients with centrally located primary 
      bronchopulmonary tumors. METHODS: Between 2000 and 2009, 36 patients with primary 
      lung tumors required bronchoplasty were retrospectively analyzed. Preoperative 
      assessment included computed tomography (CT) of the chest, bronchoscopy, and 
      spirometry. Pre operative diagnosis was acheived by bronchoscopy for all 
      patients, mediastinoscopy was done for patients with primary lung cancer. Neo 
      adjuvant chemotherapy was given for 6 patients with non small cell lung cancer 
      (NSCLC). RESULTS: We had 15 males and 21 female, the mean age was 37 years and 
      the mean hospital stay was 7.2 days. Operative procedures performed were:Sleeve 
      lobectomy in 30 patients (13 right, 17 left), partial sleeve right pneumonectomy 
      in 3 and bronchial resection with reanastomosis in 3 (2 left, 1 right). Twelve 
      patients (33.3%) suffered post-operative problems. There was one operative 
      related mortality. Post operative pathology revealed: 27 patients with typical 
      carcinoid, 2 with atypical carcinoid, 4 with squamous cell carcinoma, 2 with 
      adenocarcinoma and one with hamartoma. Pathological TNM staging revealed: 17 
      patients with stage IA, 11 with IB, 5 with IIA and 2 with stage IIIA. Follow-up 
      data were available for all patients except two. Two patients died with 
      disseminated disease 1.5 year and 2 years after surgery. The patient with 
      hamartoma developed local recurrence 5 years later and re-excision was done. One 
      patient with lung cancer developed bone metastases and was alive with disease, 
      while the remaining 30 patients were alive and disease free. The overall 5 years 
      survival was 83.3%. CONCLUSION: Bronchoplastic resections achieve local control 
      and long-term survival comparable to the standard resections in patients with 
      carcinoid tumor and NSCLC in anatomically suited lesions. KEY WORDS: 
      Bronchoplasty - Primary - Lung - Tumors.
FAU - Abdel Rahman, Abdel Rahman M
AU  - Abdel Rahman AR
AD  - The Department of Surgery, National Cancer Institute, Cairo University, Cairo, 
      Egypt.
LA  - eng
PT  - Journal Article
PL  - England
TA  - J Egypt Natl Canc Inst
JT  - Journal of the Egyptian National Cancer Institute
JID - 9424566
EDAT- 2011/04/20 06:00
MHDA- 2011/04/20 06:01
CRDT- 2011/04/20 06:00
PHST- 2011/04/20 06:00 [entrez]
PHST- 2011/04/20 06:00 [pubmed]
PHST- 2011/04/20 06:01 [medline]
PST - ppublish
SO  - J Egypt Natl Canc Inst. 2010 Mar;22(1):73-8.