PMID- 21505579
OWN - NLM
STAT- MEDLINE
DCOM- 20110602
LR  - 20220311
IS  - 1844-122X (Print)
IS  - 1844-3117 (Electronic)
IS  - 1844-122X (Linking)
VI  - 4
IP  - 1
DP  - 2011 Jan-Mar
TI  - Atrial septal defect in an elderly woman-a case report.
PG  - 91-3
AB  - RATIONALE: The atrial septal defect is one of the most common congenital 
      anomalies in adults, but it is rarely diagnosed. It is characterized by a defect 
      in the interatrial septum that allows pulmonary venous return to pass from the 
      left to the right atrium. OBJECTIVE: A case of a 75-year-old female who presented 
      with dyspnea, orthopnea, lower extremities swelling and palpitations is reported 
      here. She had a 3 years history of atrial fibrillation and one-year history of 
      cardiac failure NYHA (New York Heart Association) class Ⅱ. METHODS AND RESULTS: 
      Transthoracic echocardiography revealed a dilated right atrium of 74,2 mm, a 
      dilated left atrium of 55,2 mm, a dilated left ventricle of 64/72,3 mm, a dilated 
      right ventricle of 44,4 mm. Atrial septal defect ostium secundum type, with 
      left-to-right shunt. Severe tricuspid insufficiency with a maximum gradient of 
      55,4 mm Hg. 4th degree mitral insufficiency. Severe pulmonary hypertension of 75 
      mm Hg. The ejection fraction of 29%. Atrial fibrillation. Interventricular sept 
      with paradoxical motion. DISCUSSION: Ostium secundum defect is the most common 
      type of atrial septal defect and accounts for 60-70% of all cases. The 
      malformation often goes unnoticed for decades because symptoms may be absent and 
      because physical signs are subtle. Symptoms usually take 30-40 years to develop. 
      They are the consequences of pulmonary hypertension, atrial tachyarrhythmias and, 
      sometimes, associated mitral valve disease. The echocardiography can establish 
      the size and location of the atrial septal defect, the magnitude and hemodynamic 
      impact of the left-to-right shunt, and the presence and degree of pulmonary 
      hypertension. The particularity of this case is that the patient lived for over 
      70 years almost asymptomatic.
FAU - Diaconu, C C
AU  - Diaconu CC
AD  - Carol Davila University of Medicine and Pharmacy, Bucharest, Romania. 
      camiluciemi@yahoo.com
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20110225
PL  - Romania
TA  - J Med Life
JT  - Journal of medicine and life
JID - 101477617
SB  - IM
MH  - Aged
MH  - Echocardiography
MH  - Female
MH  - Heart Septal Defects, Atrial/*diagnostic imaging
MH  - Humans
PMC - PMC3056427
OTO - NOTNLM
OT  - echocardiography
OT  - malformation
OT  - transthoracic
EDAT- 2011/04/21 06:00
MHDA- 2011/06/03 06:00
PMCR- 2011/04/15
CRDT- 2011/04/21 06:00
PHST- 2010/10/15 00:00 [received]
PHST- 2011/01/22 00:00 [accepted]
PHST- 2011/04/21 06:00 [entrez]
PHST- 2011/04/21 06:00 [pubmed]
PHST- 2011/06/03 06:00 [medline]
PHST- 2011/04/15 00:00 [pmc-release]
AID - JMedLife-04-91 [pii]
PST - ppublish
SO  - J Med Life. 2011 Jan-Mar;4(1):91-3. Epub 2011 Feb 25.