PMID- 21509214 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20110714 LR - 20240320 IS - 2075-0528 (Electronic) IS - 2075-051X (Print) IS - 2075-051X (Linking) VI - 11 IP - 1 DP - 2011 Feb TI - Unmasking Immune Reconstitution Inflammatory Syndrome (IRIS): A report of five cases and review of the literature. PG - 95-103 AB - Immune reconstitution inflammatory syndromes (IRIS) in patients with acquired immune deficiency syndrome (AIDS) are characterised by atypical manifestations of opportunistic pathogens. These occur in patients experiencing improvement in CD4 cell counts following receipt of highly active anti-retroviral therapy (HAART). Although well established as a syndrome, IRIS still presents challenges in diagnosis and management. We report five cases of IRIS with diverse clinical presentations and due to different infectious aetiologies. A review of the published literature on this syndrome is also included. FAU - Balkhair, Abdullah AU - Balkhair A AD - Department of Medicine, Sultan Qaboos University Hospital, Muscat, Oman. FAU - Ahamed, Sudheer AU - Ahamed S FAU - Sankhla, Dilip AU - Sankhla D LA - eng PT - Journal Article DEP - 20110212 PL - Oman TA - Sultan Qaboos Univ Med J JT - Sultan Qaboos University medical journal JID - 101519915 PMC - PMC3074677 OTO - NOTNLM OT - AIDS OT - Atypical mycobacterium OT - Case report OT - Cryptococcus OT - Cryptosporidium OT - HAART OT - HIV OT - IRIS OT - Immune reconstitution inflammatory syndrome OT - Oman OT - TB OT - Toxoplasmosis EDAT- 2011/04/22 06:00 MHDA- 2011/04/22 06:01 PMCR- 2011/02/01 CRDT- 2011/04/22 06:00 PHST- 2009/11/04 00:00 [received] PHST- 2010/06/22 00:00 [revised] PHST- 2010/07/28 00:00 [revised] PHST- 2010/11/06 00:00 [accepted] PHST- 2011/04/22 06:00 [entrez] PHST- 2011/04/22 06:00 [pubmed] PHST- 2011/04/22 06:01 [medline] PHST- 2011/02/01 00:00 [pmc-release] AID - squmj-11-95 [pii] PST - ppublish SO - Sultan Qaboos Univ Med J. 2011 Feb;11(1):95-103. Epub 2011 Feb 12.