PMID- 21519102 OWN - NLM STAT- MEDLINE DCOM- 20120912 LR - 20120629 IS - 1941-0506 (Electronic) IS - 1077-2626 (Linking) VI - 18 IP - 6 DP - 2012 Jun TI - Analysis of time-dependent flow-sensitive PC-MRI data. PG - 966-77 LID - 10.1109/TVCG.2011.80 [doi] AB - Many flow visualization techniques, especially integration-based methods, are problematic when the measured data exhibit noise and discretization issues. Particularly, this is the case for flow-sensitive phase-contrast magnetic resonance imaging (PC-MRI) data sets which not only record anatomic information, but also time-varying flow information. We propose a novel approach for the visualization of such data sets using integration-based methods. Our ideas are based upon finite-time Lyapunov exponents (FTLE) and enable identification of vessel boundaries in the data as high regions of separation. This allows us to correctly restrict integration-based visualization to blood vessels. We validate our technique by comparing our approach to existing anatomy-based methods as well as addressing the benefits and limitations of using FTLE to restrict flow. We also discuss the importance of parameters, i.e., advection length and data resolution, in establishing a well-defined vessel boundary. We extract appropriate flow lines and surfaces that enable the visualization of blood flow within the vessels. We further enhance the visualization by analyzing flow behavior in the seeded region and generating simplified depictions. FAU - Krishnan, Harinarayan AU - Krishnan H AD - University of California, Davis, Davis, CA 95616, USA. hkrishnan@ucdavis.edu FAU - Garth, Christoph AU - Garth C FAU - Guhring, Jens AU - Guhring J FAU - Gulsun, M Akif AU - Gulsun MA FAU - Greiser, Andreas AU - Greiser A FAU - Joy, Kenneth I AU - Joy KI LA - eng PT - Journal Article PT - Research Support, U.S. Gov't, Non-P.H.S. PL - United States TA - IEEE Trans Vis Comput Graph JT - IEEE transactions on visualization and computer graphics JID - 9891704 SB - IM MH - Algorithms MH - Blood Flow Velocity MH - *Computer Graphics MH - Humans MH - Image Processing, Computer-Assisted/*methods MH - Magnetic Resonance Angiography/*methods MH - *Models, Cardiovascular MH - Thorax/anatomy & histology/blood supply EDAT- 2011/04/27 06:00 MHDA- 2012/09/13 06:00 CRDT- 2011/04/27 06:00 PHST- 2011/04/27 06:00 [entrez] PHST- 2011/04/27 06:00 [pubmed] PHST- 2012/09/13 06:00 [medline] AID - 10.1109/TVCG.2011.80 [doi] PST - ppublish SO - IEEE Trans Vis Comput Graph. 2012 Jun;18(6):966-77. doi: 10.1109/TVCG.2011.80.