PMID- 2151926
OWN - NLM
STAT- MEDLINE
DCOM- 19920225
LR  - 20041117
IS  - 0955-9701 (Print)
VI  - 1
IP  - 6
DP  - 1990
TI  - Human leukocyte antigens as markers of predisposition to ischaemic heart disease 
      in Russian and Georgian populations.
PG  - 639-41
AB  - The peculiarities of human leukocyte antigen (HLA) distribution (classes I and 
      II) in young Georgians (72 patients) and Russians (81 patients) with ischaemic 
      heart disease (IHD) were examined by standard tissue-typing methods. The 
      distributions of HLAs in 267 healthy Russian, and 579 healthy Georgian blood 
      donors were taken as controls. The antigens identified as genetic markers of IHD 
      predisposition among Russians were B12 (relative risk, Rr = 2.91), DR1 (Rr = 
      3.41), and DR4 (Rr = 3.14), for Georgians B21 (Rr = 6.61) was identified. The 
      difference in predisposition markers between these two populations, both 
      belonging to the same race, indicates that IHD predisposition can be linked with 
      different HLAs in different populations.
FAU - Polyanskaya, I S
AU  - Polyanskaya IS
AD  - Institute of Immunology, Ministry of Public Health, Moscow.
FAU - Alekseev, L P
AU  - Alekseev LP
FAU - Yazdovskii, V V
AU  - Yazdovskii VV
LA  - eng
PT  - Journal Article
PL  - England
TA  - Biomed Sci
JT  - Biomedical science
JID - 9010320
RN  - 0 (HLA Antigens)
RN  - 0 (HLA-A Antigens)
RN  - 0 (HLA-B Antigens)
RN  - 0 (HLA-DR Antigens)
SB  - IM
MH  - Adult
MH  - Coronary Disease/*diagnosis/immunology
MH  - Female
MH  - Georgia (Republic)
MH  - HLA Antigens/*analysis
MH  - HLA-A Antigens/analysis
MH  - HLA-B Antigens/analysis
MH  - HLA-DR Antigens/analysis
MH  - Humans
MH  - Immunophenotyping
MH  - Male
MH  - Russia
EDAT- 1990/01/01 00:00
MHDA- 1990/01/01 00:01
CRDT- 1990/01/01 00:00
PHST- 1990/01/01 00:00 [pubmed]
PHST- 1990/01/01 00:01 [medline]
PHST- 1990/01/01 00:00 [entrez]
PST - ppublish
SO  - Biomed Sci. 1990;1(6):639-41.