PMID- 21530096
OWN - NLM
STAT- MEDLINE
DCOM- 20110912
LR  - 20110523
IS  - 1873-4138 (Electronic)
IS  - 0309-1740 (Linking)
VI  - 89
IP  - 1
DP  - 2011 Sep
TI  - Polymorphism and expression of the porcine Tenascin C gene associated with meat 
      and carcass quality.
PG  - 76-83
LID - 10.1016/j.meatsci.2011.04.001 [doi]
AB  - The research aimed to screen for polymorphism, expression of Tenascin C (TNC) and 
      association with meat and carcass quality traits. Three single nucleotide 
      polymorphisms were detected. In a DurocxPietrain F2 cross (DuPi) population, 
      g.44488C>T was associated with meat color and ham weight; g.68794A>G was 
      associated with pH at 24h post mortem in ham (pH24(H)) and muscle area but 
      g.68841C>T was not statistically associated. Genotyping in a commercial Pietrain 
      (Pi) population showed that g.44488C>T was associated with pH24(H), whereas 
      g.68794A>G was associated with conductivity at 45 min post mortem in loin and 
      backfat thickness. Diplotypes showed significant effects on pH24(H) in both 
      populations. The expression was associated with pH at 45 min post mortem in loin 
      and cooking loss. TNC was significantly higher in animals with higher muscle pH. 
      Linkage analysis revealed four trans-regulated eQTL on four autosomes. These 
      results suggest that TNC could be a potential candidate gene for meat quality 
      traits in pigs.
CI  - Copyright (c) 2011 Elsevier Ltd. All rights reserved.
FAU - Kayan, A
AU  - Kayan A
AD  - Institute of Animal Science, Animal Breeding and Husbandry Group, University of 
      Bonn, 53115 Bonn, Germany. akay@itw.uni-bonn.de
FAU - Cinar, M U
AU  - Cinar MU
FAU - Uddin, M J
AU  - Uddin MJ
FAU - Phatsara, C
AU  - Phatsara C
FAU - Wimmers, K
AU  - Wimmers K
FAU - Ponsuksili, S
AU  - Ponsuksili S
FAU - Tesfaye, D
AU  - Tesfaye D
FAU - Looft, C
AU  - Looft C
FAU - Juengst, H
AU  - Juengst H
FAU - Tholen, E
AU  - Tholen E
FAU - Schellander, K
AU  - Schellander K
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20110409
PL  - England
TA  - Meat Sci
JT  - Meat science
JID - 101160862
RN  - 0 (Genetic Markers)
RN  - 0 (RNA, Messenger)
RN  - 0 (Tenascin)
SB  - IM
MH  - Animals
MH  - Body Composition
MH  - Cooking
MH  - Gene Expression Regulation
MH  - Gene Frequency
MH  - Genetic Association Studies
MH  - Genetic Linkage
MH  - Genetic Markers
MH  - Genotype
MH  - Haplotypes
MH  - *Meat
MH  - *Polymorphism, Single Nucleotide
MH  - Quantitative Trait, Heritable
MH  - RNA, Messenger/genetics/metabolism
MH  - Sus scrofa/*genetics
MH  - Tenascin/*genetics/metabolism
EDAT- 2011/05/03 06:00
MHDA- 2011/09/13 06:00
CRDT- 2011/05/03 06:00
PHST- 2010/12/17 00:00 [received]
PHST- 2011/03/30 00:00 [revised]
PHST- 2011/04/01 00:00 [accepted]
PHST- 2011/05/03 06:00 [entrez]
PHST- 2011/05/03 06:00 [pubmed]
PHST- 2011/09/13 06:00 [medline]
AID - S0309-1740(11)00127-6 [pii]
AID - 10.1016/j.meatsci.2011.04.001 [doi]
PST - ppublish
SO  - Meat Sci. 2011 Sep;89(1):76-83. doi: 10.1016/j.meatsci.2011.04.001. Epub 2011 Apr 
      9.