PMID- 21533463
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20121002
LR  - 20190606
IS  - 1019-6439 (Print)
IS  - 1019-6439 (Linking)
VI  - 10
IP  - 5
DP  - 1997 May
TI  - The peripheral myelin protein 22 kDa (PMP22) gene is amplified in cell lines 
      derived from glioma and osteogenic sarcoma.
PG  - 915-9
AB  - Two glioma (SF188, SF763) and two osteogenic sarcoma cell lines (RH30, SA1) were 
      examined for the presence of an amplification of the PMP22 gene by means of 
      fluorescence in situ hybridization (FISH). In one cell line of both cell types, 
      we found about 10 copies of the PMP22 (peripheral myelin protein 22 kDa) gene, 
      located on different marker chromosomes within homogeneously staining regions. 
      Surrounding chromosome 17p material was found to be coamplified, but 
      coamplification of TP53 (17p13) and erbB2/Her2 (17q11.12) were excluded by FISH 
      for both cell lines, SF763 and RH30. This is the first report of a PMP22 
      amplification in cell lines derived from human tumors.
FAU - Liehr, T
AU  - Liehr T
AD  - UNIV ERLANGEN NURNBERG,INST HUMAN GENET,D-91054 ERLANGEN,GERMANY. UNIV CALIF SAN 
      FRANCISCO,BRAIN TUMOR RES CTR,SAN FRANCISCO,CA 94143. UNIV CALIF SAN 
      FRANCISCO,DEPT LAB MED,SAN FRANCISCO,CA 94143.
FAU - Park, O
AU  - Park O
FAU - Feuerstein, B
AU  - Feuerstein B
FAU - Gebhart, E
AU  - Gebhart E
FAU - Rautenstrauss, B
AU  - Rautenstrauss B
LA  - eng
PT  - Journal Article
PL  - Greece
TA  - Int J Oncol
JT  - International journal of oncology
JID - 9306042
EDAT- 1997/05/01 00:00
MHDA- 1997/05/01 00:01
CRDT- 2011/05/03 06:00
PHST- 2011/05/03 06:00 [entrez]
PHST- 1997/05/01 00:00 [pubmed]
PHST- 1997/05/01 00:01 [medline]
AID - 10.3892/ijo.10.5.915 [doi]
PST - ppublish
SO  - Int J Oncol. 1997 May;10(5):915-9. doi: 10.3892/ijo.10.5.915.