PMID- 21534892
OWN - NLM
STAT- MEDLINE
DCOM- 20111220
LR  - 20110718
IS  - 1651-1980 (Electronic)
IS  - 0036-5548 (Linking)
VI  - 43
IP  - 8
DP  - 2011 Aug
TI  - Cryptococcal lymphadenitis and immune reconstitution inflammatory syndrome: 
      current considerations.
PG  - 664-8
LID - 10.3109/00365548.2011.574293 [doi]
AB  - HIV-related immune reconstitution inflammatory syndrome (IRIS) is increasingly 
      being recognized in regions with a high burden of opportunistic infections. We 
      describe an unusual manifestation of IRIS- 'unmasking' cryptococcal lymphadenitis 
      in a patient shortly after initiation of antiretroviral therapy. Epidemiology, 
      clinical features and management of cryptococcal IRIS with reference to 
      lymphadenitis presentation are briefly reviewed. Early and accurate diagnosis is 
      essential for appropriate management. Standard antifungal therapy along with 
      continuation of antiretroviral therapy is recommended. Cases with severe 
      inflammation may benefit from anti-inflammatory drugs/corticosteroids. Unusual 
      manifestations like lymphadenitis pose diagnostic difficulties in regions with a 
      high prevalence of tubercular lymphadenitis.
FAU - Kuttiatt, Vijesh
AU  - Kuttiatt V
AD  - Department of Paediatrics, St John's National Academy of Health Sciences, 
      Bangalore, India. anitashet@gmail.com
FAU - Sreenivasa, Prarthana
AU  - Sreenivasa P
FAU - Garg, Isha
AU  - Garg I
FAU - Shet, Anita
AU  - Shet A
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20110502
PL  - England
TA  - Scand J Infect Dis
JT  - Scandinavian journal of infectious diseases
JID - 0215333
RN  - 0 (Anti-Retroviral Agents)
RN  - 0 (Antifungal Agents)
SB  - IM
MH  - AIDS-Related Opportunistic Infections/*diagnosis/drug 
      therapy/microbiology/pathology
MH  - Adult
MH  - Anti-Retroviral Agents/therapeutic use
MH  - Antifungal Agents/therapeutic use
MH  - Cryptococcosis/*diagnosis/drug therapy/microbiology/pathology
MH  - Cryptococcus/isolation & purification
MH  - Humans
MH  - Immune Reconstitution Inflammatory Syndrome/*diagnosis/microbiology/pathology
MH  - Lymphadenitis/*diagnosis/drug therapy/microbiology/pathology
MH  - Male
EDAT- 2011/05/04 06:00
MHDA- 2011/12/21 06:00
CRDT- 2011/05/04 06:00
PHST- 2011/05/04 06:00 [entrez]
PHST- 2011/05/04 06:00 [pubmed]
PHST- 2011/12/21 06:00 [medline]
AID - 10.3109/00365548.2011.574293 [doi]
PST - ppublish
SO  - Scand J Infect Dis. 2011 Aug;43(8):664-8. doi: 10.3109/00365548.2011.574293. Epub 
      2011 May 2.