PMID- 21548212
OWN - NLM
STAT- MEDLINE
DCOM- 20111115
LR  - 20110506
IS  - 1009-3591 (Print)
IS  - 1009-3591 (Linking)
VI  - 17
IP  - 4
DP  - 2011 Apr
TI  - [Clinicopathological analysis of testicular mixed germ cell tumor].
PG  - 336-41
AB  - OBJECTIVE: To investigate the clinicopathological characteristics of primary 
      testicular mixed germ cell tumor (MGCT). METHODS: We retrospectively analyzed the 
      clinicopathological data of 13 cases of primary testicular MGCT and reviewed 
      other relevant literature. RESULTS: MGCT accounted for 24.1% (13/54) of all the 
      testicular germ cell tumors diagnosed in our hospital. The patients ranged in age 
      from 2 to 53 years, averaging at 28.3 years. All were unilateral cases, 6 in the 
      left and 7 in the right testis, with a left/right ratio of 0.86:1. 
      Morphologically, testicular MGCT displayed a variety of subtypes, embryonal 
      carcinoma in 11 cases (84.6%), seminoma in 8 (61.5%), teratoma in 6 (46.2%), 
      choriocarcinoma in 4 (30.8%) and yolk sac tumor in 4 (30.8%). Nine of the cases 
      (69.2%) were composed of two different germ cell histological elements, 3 (23.1%) 
      composed of three, and 1 (7.7%) composed of five. CONCLUSION: Testicular MGCT is 
      rather rare and most commonly occurs in young men. Its biological behavior, 
      clinical management and prognosis vary with its different histological elements. 
      Therefore accurate pathological diagnosis is essential and immunohistochemistry 
      plays an important role in the diagnosis and differential diagnosis of testicular 
      MGCT.
FAU - Zhang, Chun-Fang
AU  - Zhang CF
AD  - Department of Pathology, Nanjing General Hospital of Nanjing Military Region, 
      Nanjing, Jiangsu 210002, China. zcf_314@yahoo.cn
FAU - Liu, Chong
AU  - Liu C
FAU - Shi, Qun-Li
AU  - Shi QL
FAU - Ma, Jie
AU  - Ma J
FAU - Ma, Heng-Hui
AU  - Ma HH
FAU - Zhou, Hang-Bo
AU  - Zhou HB
LA  - chi
PT  - English Abstract
PT  - Journal Article
PL  - China
TA  - Zhonghua Nan Ke Xue
JT  - Zhonghua nan ke xue = National journal of andrology
JID - 101093592
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Child
MH  - Child, Preschool
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Neoplasms, Germ Cell and Embryonal/*pathology
MH  - Retrospective Studies
MH  - Testicular Neoplasms/*pathology
MH  - Young Adult
EDAT- 2011/05/10 06:00
MHDA- 2011/11/16 06:00
CRDT- 2011/05/10 06:00
PHST- 2011/05/10 06:00 [entrez]
PHST- 2011/05/10 06:00 [pubmed]
PHST- 2011/11/16 06:00 [medline]
PST - ppublish
SO  - Zhonghua Nan Ke Xue. 2011 Apr;17(4):336-41.