PMID- 2154866
OWN - NLM
STAT- MEDLINE
DCOM- 19900328
LR  - 20061115
IS  - 0148-5717 (Print)
IS  - 0148-5717 (Linking)
VI  - 17
IP  - 1
DP  - 1990 Jan-Mar
TI  - Restriction endonuclease analysis of deoxyribonucleic acid (DNA) from genital 
      herpes simplex virus type 2 isolates in Thailand.
PG  - 42-7
AB  - Local herpes simplex virus (HSV) isolates were characterized by the use of BamHI, 
      KpnI, and EcoRI restriction endonucleases. Analysis of 120 clinical isolates by 
      observation of presence or absence of cleavage sites and of mobility variation in 
      deoxyribonucleic acid (DNA) fragments from the terminal and joint regions of the 
      HSV genome revealed that 112 (93.3%) were type-2 (HSV-2) and the others were 
      type-1 (HSV-1), mixed HSV-2 and HSV-1, and mixed HSV-2 strains. The genomes of 
      HSV-2 isolates were highly conserved and could be classified into 25 distinct 
      restriction endonuclease (RE) cleavage patterns, which differed from those 
      obtained with isolates of other countries.
FAU - Chantratita, W
AU  - Chantratita W
AD  - Department of Microbiology, Faculty of Science, Mahidol University, Bangkok, 
      Thailand.
FAU - Yoosook, C
AU  - Yoosook C
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Sex Transm Dis
JT  - Sexually transmitted diseases
JID - 7705941
RN  - 0 (DNA, Viral)
RN  - EC 3.1.21.- (DNA Restriction Enzymes)
SB  - IM
MH  - DNA Restriction Enzymes/*analysis
MH  - DNA, Viral/*analysis
MH  - Female
MH  - Herpes Genitalis/microbiology
MH  - Humans
MH  - Male
MH  - Simplexvirus/*classification/enzymology/isolation & purification
MH  - Thailand
EDAT- 1990/01/01 00:00
MHDA- 1990/01/01 00:01
CRDT- 1990/01/01 00:00
PHST- 1990/01/01 00:00 [pubmed]
PHST- 1990/01/01 00:01 [medline]
PHST- 1990/01/01 00:00 [entrez]
PST - ppublish
SO  - Sex Transm Dis. 1990 Jan-Mar;17(1):42-7.