PMID- 21556736 OWN - NLM STAT- MEDLINE DCOM- 20120828 LR - 20211020 IS - 1573-2576 (Electronic) IS - 0360-3997 (Linking) VI - 35 IP - 2 DP - 2012 Apr TI - Evaluation of the inflammatory response to two different intensities of exercise in individuals with heart failure. PG - 509-15 LID - 10.1007/s10753-011-9339-z [doi] AB - The aim of this study is to compare the response of interleukin-6 (IL-6) and soluble tumor necrosis factor alpha receptor 1 (s-TNFr1) to two submaximal intensities of exercise in individuals with heart failure (HF). Thirty-two HF individuals aged 45.53 +/- 9.41 years, classes II and III of the New York Heart Association (NYHA) classification underwent two sessions of exercise at low and moderate intensities with blood analysis at baseline, exercise and after exercise. The differences were evaluated by Friedman test and factorial ANOVA. Alpha = 5% was considered. No difference in IL-6 was detected for low intensity. At moderate intensity, there was a significant increase after exercise. The s-TNFr1 increased in moderate-intensity exercise and went back to baseline levels after it. A session of moderate-intensity exercise is better than low-intensity exercise at promoting positive immediate inflammatory responses in individuals with HF class II and III of the NYHA. FAU - Pereira, Danielle Aparecida Gomes AU - Pereira DA AD - Physical Therapy Department, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil. d.fisio@ig.com.br FAU - Ribeiro-Samora, Giane Amorim AU - Ribeiro-Samora GA FAU - Vieira, Danielle Soares Rocha AU - Vieira DS FAU - Pereira, Leani Souza Maximo AU - Pereira LS FAU - Coelho, Fernanda Matos AU - Coelho FM FAU - Parreira, Veronica Franco AU - Parreira VF FAU - Moreira, Maria da Consolacao Vieira AU - Moreira Mda C FAU - Alencar, Maria Clara Noman AU - Alencar MC FAU - Britto, Raquel Rodrigues AU - Britto RR LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - Inflammation JT - Inflammation JID - 7600105 RN - 0 (Interleukin-6) RN - 0 (Receptors, Tumor Necrosis Factor, Type I) SB - IM MH - Adult MH - *Exercise MH - Exercise Test MH - Female MH - Heart Failure/*immunology MH - Humans MH - Inflammation MH - Interleukin-6/*blood MH - Male MH - Middle Aged MH - Receptors, Tumor Necrosis Factor, Type I/*blood EDAT- 2011/05/11 06:00 MHDA- 2012/08/29 06:00 CRDT- 2011/05/11 06:00 PHST- 2011/05/11 06:00 [entrez] PHST- 2011/05/11 06:00 [pubmed] PHST- 2012/08/29 06:00 [medline] AID - 10.1007/s10753-011-9339-z [doi] PST - ppublish SO - Inflammation. 2012 Apr;35(2):509-15. doi: 10.1007/s10753-011-9339-z.