PMID- 21558854
OWN - NLM
STAT- MEDLINE
DCOM- 20111209
LR  - 20110804
IS  - 1473-5830 (Electronic)
IS  - 0954-6928 (Linking)
VI  - 22
IP  - 6
DP  - 2011
TI  - Patients with anemia on admission who have undergone primary angioplasty for ST 
      elevation myocardial infarction: in-hospital and long-term clinical outcomes.
PG  - 375-9
LID - 10.1097/MCA.0b013e3283472ac5 [doi]
AB  - OBJECTIVE: We investigated the in-hospital and long-term follow-up (mean 21 
      months) results of patients with and without anemia on admission and who have 
      undergone primary angioplasty for ST elevation myocardial infarction (STEMI). 
      STUDY DESIGN: A total of 2509 patients (616 patients with anemia on admission, 
      1893 patients without anemia on admission), who were treated with primary 
      angioplasty due to STEMI, were included in this study. Demographics and basic 
      clinical features of the patients, outcomes of the primary angioplasty 
      procedures, and clinical course of the patients during and a mean period of 
      21-month follow-up after hospitalization were retrospectively evaluated. All the 
      parameters were compared between anemic and nonanemic groups. RESULTS: The mean 
      age of the patients in anemic group was found to be higher than nonanemic group 
      (61.5 +/- 11.4 vs. 54.8 +/- 11.4, P<0.001). The rates of death, major cardiac events, 
      and severe cardiac insufficiency were significantly higher in anemic patients 
      during hospitalization period. Moreover, frequency of death was also higher in 
      anemic patients when compared with the nonanemic ones after a mean follow-up 
      period of 21 months (P<0.001). Anemia on admission is an independent predictive 
      factor for mortality in patients with STEMI who were treated with primary 
      angioplasty (odds ratio: 2.2; 95% confidence interval: 1.2-4.0; P<0.009). 
      CONCLUSION: Patients with anemia on admission initially have high-risk profiles 
      regarding their worse clinical outcomes during and 21 months after 
      hospitalization. In accordance with the suggestion of the evidence-based medicine 
      we conclude that etiology of anemia should be meticulously investigated and the 
      oxygenization of the tissue should be provided with the appropriate treatment.
FAU - Ayhan, Erkan
AU  - Ayhan E
AD  - Department of Cardiology, Dr Siyami Ersek Thoracic and Cardiovascular Surgery 
      Center, Training and Research Hospital, Istanbul, Turkey. erkayh@gmail.com
FAU - Aycicek, Fatih
AU  - Aycicek F
FAU - Uyarel, Huseyin
AU  - Uyarel H
FAU - Ergelen, Mehmet
AU  - Ergelen M
FAU - Cicek, Gokhan
AU  - Cicek G
FAU - Gul, Mehmet
AU  - Gul M
FAU - Osmonov, Damirbek
AU  - Osmonov D
FAU - Yildirim, Ersin
AU  - Yildirim E
FAU - Bozbay, Mehmet
AU  - Bozbay M
FAU - Ugur, Murat
AU  - Ugur M
FAU - Isik, Turgay
AU  - Isik T
FAU - Tezel, Tuna
AU  - Tezel T
LA  - eng
PT  - Journal Article
PL  - England
TA  - Coron Artery Dis
JT  - Coronary artery disease
JID - 9011445
SB  - IM
MH  - Adult
MH  - Aged
MH  - Anemia/blood/*complications/mortality
MH  - *Angioplasty, Balloon, Coronary/adverse effects/mortality
MH  - Chi-Square Distribution
MH  - Female
MH  - Heart Diseases/etiology/mortality
MH  - Hospital Mortality
MH  - Humans
MH  - Kaplan-Meier Estimate
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/blood/complications/mortality/*therapy
MH  - Odds Ratio
MH  - *Patient Admission
MH  - Proportional Hazards Models
MH  - Retrospective Studies
MH  - Risk Assessment
MH  - Risk Factors
MH  - Time Factors
MH  - Treatment Outcome
MH  - Turkey
EDAT- 2011/05/12 06:00
MHDA- 2011/12/14 06:00
CRDT- 2011/05/12 06:00
PHST- 2011/05/12 06:00 [entrez]
PHST- 2011/05/12 06:00 [pubmed]
PHST- 2011/12/14 06:00 [medline]
AID - 10.1097/MCA.0b013e3283472ac5 [doi]
PST - ppublish
SO  - Coron Artery Dis. 2011;22(6):375-9. doi: 10.1097/MCA.0b013e3283472ac5.