PMID- 2155915
OWN - NLM
STAT- MEDLINE
DCOM- 19900420
LR  - 20210526
IS  - 0095-1137 (Print)
IS  - 1098-660X (Electronic)
IS  - 0095-1137 (Linking)
VI  - 28
IP  - 2
DP  - 1990 Feb
TI  - Effect of primary Epstein-Barr virus infection on human herpesvirus 6, 
      cytomegalovirus, and measles virus immunoglobulin G titers.
PG  - 211-5
AB  - Immunoglobulin G antibody titers to human herpesvirus 6 (HHV-6), measles virus, 
      and cytomegalovirus (CMV) were examined in serum samples from 31 patients with 
      Epstein-Barr virus (EBV)-induced infectious mononucleosis (IM). Sera were drawn 
      sequentially from the same patients less than or equal to 7 days until 3 years 
      after onset of IM. In seropositive patients, there was a significant decrease 
      with time after IM of the immunoglobulin G titers to the three viruses in the 
      majority of patients; HHV-6 IgG titers decreased in 80%, measles virus IgG titers 
      decreased in 75%, and CMV IgG titers decreased in 67%. Four patients contracted 
      CMV infection during the observation period after IM. In these, HHV-6 IgG titers 
      increased, while EBV and measles virus IgG titers remained essentially 
      stationary. Polyclonal B-cell stimulation during IM is suggested to augment 
      antiviral titers in general, but the increases of HHV-6 IgG titers during EBV and 
      CMV infections may also be due to selective stimulation of memory B cells by 
      related antigens or to reactivation of HHV-6 during infection with these 
      herpesviruses.
FAU - Linde, A
AU  - Linde A
AD  - Department of Virology, National Bacteriological Laboratory, Stockholm, Sweden.
FAU - Fridell, E
AU  - Fridell E
FAU - Dahl, H
AU  - Dahl H
FAU - Andersson, J
AU  - Andersson J
FAU - Biberfeld, P
AU  - Biberfeld P
FAU - Wahren, B
AU  - Wahren B
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Clin Microbiol
JT  - Journal of clinical microbiology
JID - 7505564
RN  - 0 (Antibodies, Viral)
RN  - 0 (Immunoglobulin G)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Antibodies, Viral/*metabolism
MH  - Cytomegalovirus/immunology
MH  - Female
MH  - Herpesvirus 4, Human/immunology
MH  - Herpesvirus 6, Human/immunology
MH  - Humans
MH  - Immunoglobulin G/metabolism
MH  - Infectious Mononucleosis/*immunology
MH  - Male
MH  - Measles virus/immunology
MH  - Time Factors
PMC - PMC269577
EDAT- 1990/02/01 00:00
MHDA- 1990/02/01 00:01
PMCR- 1990/02/01
CRDT- 1990/02/01 00:00
PHST- 1990/02/01 00:00 [pubmed]
PHST- 1990/02/01 00:01 [medline]
PHST- 1990/02/01 00:00 [entrez]
PHST- 1990/02/01 00:00 [pmc-release]
AID - 10.1128/jcm.28.2.211-215.1990 [doi]
PST - ppublish
SO  - J Clin Microbiol. 1990 Feb;28(2):211-5. doi: 10.1128/jcm.28.2.211-215.1990.