PMID- 21565301
OWN - NLM
STAT- MEDLINE
DCOM- 20110902
LR  - 20181201
IS  - 1873-4324 (Electronic)
IS  - 0003-2670 (Linking)
VI  - 694
IP  - 1-2
DP  - 2011 May 23
TI  - Detection of antibiotic residues in bovine milk by a voltammetric electronic 
      tongue system.
PG  - 46-56
LID - 10.1016/j.aca.2011.02.053 [doi]
AB  - A voltammetric electronic tongue (VE-tongue) was developed to detect antibiotic 
      residues in bovine milk. Six antibiotics (Chloramphenicol, Erythromycin, 
      Kanamycin sulfate, Neomycin sulfate, Streptomycin sulfate and Tetracycline HCl) 
      spiked at four different concentration levels (0.5, 1, 1.5 and 2 maximum residue 
      limits (MRLs)) were classified based on VE-tongue by two pattern recognition 
      methods: principal component analysis (PCA) and discriminant function analysis 
      (DFA). The VE-tongue was composed of five working electrodes (gold, silver, 
      platinum, palladium, and titanium) positioned in a standard three-electrode 
      configuration. The Multi-frequency large amplitude pulse voltammetry (MLAPV) 
      which consisted of four segments (1 Hz, 10 Hz, 100 Hz and 1000 Hz) was applied as 
      potential waveform. The six antibiotics at the MRLs could not be separated from 
      bovine milk completely by PCA, but all the samples were demarcated clearly by 
      DFA. Three regression models: Principal Component Regression Analysis (PCR), 
      Partial Least Squares Regression (PLSR), and Least Squares-Support Vector 
      Machines (LS-SVM) were used for concentrations of antibiotics prediction. All the 
      regression models performed well, and PCR had the most stable results.
CI  - Copyright (c) 2011 Elsevier B.V. All rights reserved.
FAU - Wei, Zhenbo
AU  - Wei Z
AD  - Zhejiang University, Department of Bio-Systems Engineering, Hangzhou, Zhejiang, 
      China.
FAU - Wang, Jun
AU  - Wang J
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20110302
PL  - Netherlands
TA  - Anal Chim Acta
JT  - Analytica chimica acta
JID - 0370534
RN  - 0 (Anti-Bacterial Agents)
RN  - 59-01-8 (Kanamycin)
RN  - 63937KV33D (Erythromycin)
RN  - 66974FR9Q1 (Chloramphenicol)
RN  - F8VB5M810T (Tetracycline)
RN  - I16QD7X297 (Neomycin)
RN  - Y45QSO73OB (Streptomycin)
SB  - IM
MH  - Animals
MH  - Anti-Bacterial Agents/*analysis
MH  - Cattle
MH  - Chloramphenicol/analysis
MH  - Discriminant Analysis
MH  - Electrochemical Techniques/*methods
MH  - Electrodes
MH  - Erythromycin/analysis
MH  - Kanamycin/analysis
MH  - Least-Squares Analysis
MH  - Milk/*chemistry
MH  - Neomycin/analysis
MH  - Principal Component Analysis
MH  - Streptomycin/analysis
MH  - Tetracycline/analysis
EDAT- 2011/05/14 06:00
MHDA- 2011/09/03 06:00
CRDT- 2011/05/14 06:00
PHST- 2010/10/21 00:00 [received]
PHST- 2011/01/19 00:00 [revised]
PHST- 2011/02/23 00:00 [accepted]
PHST- 2011/05/14 06:00 [entrez]
PHST- 2011/05/14 06:00 [pubmed]
PHST- 2011/09/03 06:00 [medline]
AID - S0003-2670(11)00278-9 [pii]
AID - 10.1016/j.aca.2011.02.053 [doi]
PST - ppublish
SO  - Anal Chim Acta. 2011 May 23;694(1-2):46-56. doi: 10.1016/j.aca.2011.02.053. Epub 
      2011 Mar 2.