PMID- 21566782
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20110714
LR  - 20211020
IS  - 2008-8213 (Electronic)
IS  - 2008-7802 (Print)
IS  - 2008-7802 (Linking)
VI  - 1
IP  - 4
DP  - 2010 Fall
TI  - Assessment of clopidogrel on the left ventricular ejection fraction in acute 
      myocardial infarction.
PG  - 257-9
AB  - OBJECTIVES: Left ventricular (LV) dysfunction heart failure is one of the causes 
      of morbidity and mortality following ST elevation myocardial infarction (STEMI). 
      This study was done to determine the clopidogrel effect in preventing reduced LV 
      function in patients with STEMI. METHODS: In this study, 144 patients with STEMI 
      admitted to the Isfahan University of Medical Sciences hospitals were followed in 
      two groups for one month. The case group received Clopidogrel, 300 mg, on 
      admission and then, 75 mg daily, while the control group received routine therapy 
      for STEMI without Clopidogrel. Left ventricular ejection fraction (LVEF) on the 
      4(th) day and one month after STEMI was measured by echocardiography. The results 
      of LVEF were compared within and between groups. RESULTS: The mean LVEF in the 
      case group on the 4(th) day and one month after STEMI were 45.92 and 52.15%, 
      respectively (P<0.001). The mean LVEF in the control group on 4(th) day and one 
      month after STEMI were 44.72 and 42.71%, respectively. CONCLUSIONS: We suggest 
      that Clopidogrel is effective in prevention of LVEF reduction in patients with 
      STEMI.
FAU - Khosravi, Pejman
AU  - Khosravi P
AD  - Clinical Resident, Department of Internal Medicine, School of Medicine, Isfahan 
      University of Medical Sciences (IUMS), Isfahan, Iran.
FAU - Shemirani, Hasan
AU  - Shemirani H
FAU - Hedayatpour, Behnoud
AU  - Hedayatpour B
FAU - Golabchi, Allahyar
AU  - Golabchi A
LA  - eng
PT  - Journal Article
PL  - Iran
TA  - Int J Prev Med
JT  - International journal of preventive medicine
JID - 101535380
PMC - PMC3075522
OTO - NOTNLM
OT  - Heart failure
OT  - Myocardial infarction
OT  - Prevention
COIS- Conflict of interest statement: All authors declare that they have no conflict of 
      interest.
EDAT- 2011/05/14 06:00
MHDA- 2011/05/14 06:01
PMCR- 2010/09/01
CRDT- 2011/05/14 06:00
PHST- 2010/08/02 00:00 [received]
PHST- 2010/10/01 00:00 [accepted]
PHST- 2011/05/14 06:00 [entrez]
PHST- 2011/05/14 06:00 [pubmed]
PHST- 2011/05/14 06:01 [medline]
PHST- 2010/09/01 00:00 [pmc-release]
AID - IJPVM-1-257 [pii]
PST - ppublish
SO  - Int J Prev Med. 2010 Fall;1(4):257-9.