PMID- 21569024
OWN - NLM
STAT- MEDLINE
DCOM- 20120316
LR  - 20110727
IS  - 1528-1167 (Electronic)
IS  - 0013-9580 (Linking)
VI  - 52
IP  - 8
DP  - 2011 Aug
TI  - Language deficits and altered hemispheric lateralization in young people in 
      remission from BECTS.
PG  - e79-83
LID - 10.1111/j.1528-1167.2011.03105.x [doi]
AB  - Benign epilepsy with centrotemporal spikes (BECTS) is associated with language 
      disturbances during the active phase of the seizure disorder. However, it is not 
      yet known whether these deficits are reversible or have long-term impact on the 
      development of language skills. We report on a study conducted in 13 patients in 
      remission from BECTS and 13 age-matched controls, who underwent 
      neuropsychological assessments. We also recorded event-related potentials (ERPs) 
      during a verb generation task, to determine cortical lateralization of language. 
      The BECTS group showed significant language deficits compared to controls as well 
      as a pattern of atypical ERP lateralization in frontal regions. These findings 
      support the view that BECTS in childhood may lead to enduring effects on brain 
      maturation and language development.
CI  - Wiley Periodicals, Inc. (c) 2011 International League Against Epilepsy.
FAU - Monjauze, Cecile
AU  - Monjauze C
AD  - Developmental Cognitive Neurosciences Unit, UCL Institute of Child Health, 
      London, UK. cecile.monjauze@univ-tours.fr
FAU - Broadbent, Hannah
AU  - Broadbent H
FAU - Boyd, Stewart G
AU  - Boyd SG
FAU - Neville, Brian G R
AU  - Neville BG
FAU - Baldeweg, Torsten
AU  - Baldeweg T
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20110513
PL  - United States
TA  - Epilepsia
JT  - Epilepsia
JID - 2983306R
SB  - IM
MH  - Adolescent
MH  - Epilepsy, Rolandic/*physiopathology
MH  - Evoked Potentials
MH  - Female
MH  - *Functional Laterality
MH  - Humans
MH  - Language Development Disorders/*etiology
MH  - Male
MH  - Young Adult
EDAT- 2011/05/17 06:00
MHDA- 2012/03/17 06:00
CRDT- 2011/05/17 06:00
PHST- 2011/05/17 06:00 [entrez]
PHST- 2011/05/17 06:00 [pubmed]
PHST- 2012/03/17 06:00 [medline]
AID - 10.1111/j.1528-1167.2011.03105.x [doi]
PST - ppublish
SO  - Epilepsia. 2011 Aug;52(8):e79-83. doi: 10.1111/j.1528-1167.2011.03105.x. Epub 
      2011 May 13.