PMID- 21569801
OWN - NLM
STAT- MEDLINE
DCOM- 20111024
LR  - 20110621
IS  - 1872-7549 (Electronic)
IS  - 0166-4328 (Linking)
VI  - 223
IP  - 2
DP  - 2011 Oct 1
TI  - Differential regional brain responses to induced maternal behavior in rats 
      measured by cytochrome oxidase immunohistochemistry.
PG  - 293-6
LID - 10.1016/j.bbr.2011.04.046 [doi]
AB  - Maternal behavior (MB) in rats is expressed under neural control of vomeronasal 
      structures. Some of these regions exert an inhibitory role, such as the accessory 
      olfactory bulb (AOB), while others exert an excitatory role, such as the medial 
      preoptic area (MPOA). In previous studies, using 2-DG as a marker for neuron 
      activity at neuron terminal level, we reported that AOB showed a decrease and 
      MPOA an increase when compared with control rats (non-exposed to pups) during the 
      display of MB. In the present study we used a different indicator of neuronal 
      metabolic activity - cytochrome oxidase (COx) - to assess the activity of the 
      same brain regions in relation to induced MB. The induced-MB females showed 
      increased COx expression in the MPOA and reduced COx activity in the AOB in 
      comparison with the control, non-MB group, consistent with our previous findings 
      using 2-DG. Present results provide further evidence of a facilitatory role of 
      MPOA and an inhibitory role of AOB in MB induction.
CI  - Copyright (c) 2011 Elsevier B.V. All rights reserved.
FAU - Perez-Laso, Carmen
AU  - Perez-Laso C
AD  - Departamento de Psicobiologia, Facultad de Psicologia, UNED, 28040 Madrid, Spain.
FAU - Rubio, Sandra
AU  - Rubio S
FAU - Martin, Jose Luis R
AU  - Martin JL
FAU - Gomez, Francisco
AU  - Gomez F
FAU - Segovia, Santiago
AU  - Segovia S
FAU - Del Cerro, Ma Cruz R
AU  - Del Cerro MC
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20110505
PL  - Netherlands
TA  - Behav Brain Res
JT  - Behavioural brain research
JID - 8004872
RN  - EC 1.9.3.1 (Electron Transport Complex IV)
SB  - IM
MH  - Animals
MH  - Autoradiography
MH  - Brain/*enzymology/*physiology
MH  - Brain Chemistry/drug effects
MH  - Electron Transport Complex IV/antagonists & inhibitors/*metabolism
MH  - Female
MH  - Immunohistochemistry
MH  - Maternal Behavior/drug effects/*physiology
MH  - Olfactory Bulb/enzymology/physiology
MH  - Preoptic Area/enzymology/physiology
MH  - Rats
MH  - Rats, Wistar
EDAT- 2011/05/17 06:00
MHDA- 2011/10/25 06:00
CRDT- 2011/05/17 06:00
PHST- 2011/03/09 00:00 [received]
PHST- 2011/04/26 00:00 [revised]
PHST- 2011/04/27 00:00 [accepted]
PHST- 2011/05/17 06:00 [entrez]
PHST- 2011/05/17 06:00 [pubmed]
PHST- 2011/10/25 06:00 [medline]
AID - S0166-4328(11)00370-6 [pii]
AID - 10.1016/j.bbr.2011.04.046 [doi]
PST - ppublish
SO  - Behav Brain Res. 2011 Oct 1;223(2):293-6. doi: 10.1016/j.bbr.2011.04.046. Epub 
      2011 May 5.